Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria (Q24320251)

negative regulation of defense response to virus

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Lijuan Xu

1

0 references

Nengming Xiao

2

0 references

Feng Liu

3

0 references

Hongwei Ren

4

0 references

Jun Gu

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

3 February 2009

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published in

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volume

106

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issue

5

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page(s)

1530-5

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cites work

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SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways

19 March 2017

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

19 March 2017

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gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway

19 March 2017

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

19 March 2017

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Interactions between rubella virus capsid and host protein p32 are important for virus replication

19 March 2017

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The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

19 March 2017

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Toll-like receptor signalling

19 March 2017

1 reference

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Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation

19 March 2017

1 reference

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The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

Identification of the zinc-dependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular "heads" of C1q (gC1q-R)

19 March 2017

1 reference

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Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

19 March 2017

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Pathogen recognition and innate immunity

19 March 2017

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

19 March 2017

1 reference

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

19 March 2017

1 reference

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

19 March 2017

1 reference

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Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

19 March 2017

1 reference

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Cell type-specific involvement of RIG-I in antiviral response

7 April 2017

1 reference

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Differential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity.

7 April 2017

1 reference

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NLRX1 is a regulator of mitochondrial antiviral immunity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

Genetic analysis of resistance to viral infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

siRNA and isRNA: two edges of one sword

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

Cellular p32 recruits cytomegalovirus kinase pUL97 to redistribute the nuclear lamina

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

Type I interferons (alpha/beta) in immunity and autoimmunity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

PI3K and negative regulation of TLR signaling.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

Adenovirus core protein V interacts with p32--a protein which is associated with both the mitochondria and the nucleus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

The multiligand-binding protein gC1qR, putative C1q receptor, is a mitochondrial protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635802

Evidence that the two C1q binding membrane proteins, gC1q-R and cC1q-R, associate to form a complex

27 September 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19164550

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure and function of gC1q-R: a multiligand binding cellular protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19164550

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Retargeting of the mitochondrial protein p32/gC1Qr to a cytoplasmic compartment and the cell surface

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19164550