PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1 (Q24318973)

8

object named as

Rob Michalides

0 references

Wilbert Zwart

1

object named as

Wilbert Zwart

0 references

Alexander Griekspoor

2

object named as

Alexander Griekspoor

0 references

author name string

Valeria Berno

3

0 references

Kim Lakeman

4

0 references

Michael Mancini

6

0 references

Jacques Neefjes

Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains

7

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language of work or name

English

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publication date

8 August 2007

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published in

The EMBO Journal

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volume

26

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issue

15

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page(s)

3534-44

0 references

cites work

1 reference

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

19 March 2017

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Molecular basis of agonism and antagonism in the oestrogen receptor

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A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

19 March 2017

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The coregulator exchange in transcriptional functions of nuclear receptors

19 March 2017

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P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium

19 March 2017

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Molecular determinants for the tissue specificity of SERMs

19 March 2017

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The Nuclear Corepressors NCoR and SMRT Are Key Regulators of Both Ligand- and 8-Bromo-Cyclic AMP-Dependent Transcriptional Activity of the Human Progesterone Receptor

19 March 2017

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Genome-wide analysis of estrogen receptor binding sites

19 March 2017

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A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

7 April 2017

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Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha.

7 April 2017

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Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients

27 September 2017

1 reference

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Lessons learnt from structural studies of the oestrogen receptor

27 September 2017

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Activation function-1 domain of estrogen receptor regulates the agonistic and antagonistic actions of tamoxifen

27 September 2017

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Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor

27 September 2017

1 reference

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Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape.

27 September 2017

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Inverse relationship between ER-beta and SRC-1 predicts outcome in endocrine-resistant breast cancer

27 September 2017

1 reference

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Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer

27 September 2017

1 reference

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Correcting confocal acquisition to optimize imaging of fluorescence resonance energy transfer by sensitized emission

27 September 2017

1 reference

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Review of the in vivo functions of the p160 steroid receptor coactivator family

27 September 2017

1 reference

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Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer

27 September 2017

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8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein

27 September 2017

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Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription

27 September 2017

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Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway.

27 September 2017

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The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors.

27 September 2017

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HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading

27 September 2017

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Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase

27 September 2017

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Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.

29 November 2018

1 reference

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A dynamic structural model for estrogen receptor-alpha activation by ligands, emphasizing the role of interactions between distant A and E domains

29 November 2018

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Involvement of G1/S cyclins in estrogen-independent proliferation of estrogen receptor-positive breast cancer cells

29 November 2018

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FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent

29 November 2018

1 reference

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Estrogen receptor activation function 1 works by binding p160 coactivator proteins

29 November 2018

1 reference

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Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17627277

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7601791

1 reference

1 reference

1 reference

PubMed publication ID

17627277

1 reference