The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1 (Q24316909)

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1 January 2020

title

The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1 (English)

1 reference

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Nei like DNA glycosylase 1

1 January 2020

main subject

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Werner syndrome RecQ like helicase

GOA release 2020-03-11

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negative regulation of nuclease activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Aditi Das

1

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1 January 2020

Istvan Boldogh

2

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1 January 2020

Jae Wan Lee

3

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1 January 2020

Jeanine A Harrigan

4

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1 January 2020

Jason Piotrowski

6

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1 January 2020

Nadja de Souza Pinto

7

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1 January 2020

William Ramos

8

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1 January 2020

Marc M Greenberg

9

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1 January 2020

Tapas K Hazra

10

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1 January 2020

Sankar Mitra

11

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1 January 2020

language of work or name

English

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publication date

3 July 2007

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1 January 2020

number of pages

12

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Journal of Biological Chemistry

inferred from page(s)

published in

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1 January 2020

volume

282

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issue

36

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page(s)

26591-26602

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Oxidants, antioxidants, and the degenerative diseases of aging

1 January 2020

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Oxidative stress: free radical production in neural degeneration.

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Decreased base excision repair and increased helicase activity in Alzheimer's disease brain.

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Base excision repair of DNA in mammalian cells

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The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity

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DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair

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Long-patch DNA repair synthesis during base excision repair in mammalian cells

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A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII

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Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA

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Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions

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Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA

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AP endonuclease-independent DNA base excision repair in human cells

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Repair of Oxidized Bases in DNA Bubble Structures by Human DNA Glycosylases NEIL1 and NEIL2

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Roles of the Werner syndrome protein in pathways required for maintenance of genome stability

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Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

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Current advances in unraveling the function of the Werner syndrome protein

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Regulation of WRN helicase activity in human base excision repair

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Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

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The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity

21 January 2018

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Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage

21 January 2018

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Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein

21 January 2018

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An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

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Homologous recombination resolution defect in werner syndrome

21 January 2018

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Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase

21 January 2018

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The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta

21 January 2018

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Werner syndrome protein contains three structure-specific DNA binding domains

21 January 2018

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Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo

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Mast Cell Degranulation RequiresN-Ethylmaleimide-Sensitive Factor-Mediated SNARE Disassembly

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The Werner syndrome protein is a DNA helicase

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The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death

21 January 2018

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21 January 2018

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Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein

21 January 2018

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Pathways and functions of the Werner syndrome protein

21 January 2018

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21 January 2018

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Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases

21 January 2018

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WRN helicase expression in Werner syndrome cell lines

21 January 2018

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DNA damage-induced translocation of the Werner helicase is regulated by acetylation

21 January 2018

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Werner protein protects nonproliferating cells from oxidative DNA damage

21 January 2018

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Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain

21 January 2018

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The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates NEIL1 glycosylase

21 January 2018

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Spontaneous and induced chromosomal instability in Werner syndrome

21 January 2018

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7 January 2021

Multiple involvement of oxidative stress in Werner syndrome phenotype

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https://api.crossref.org/works/10.1074/JBC.M703343200

7 January 2021

Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells

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https://api.crossref.org/works/10.1074/JBC.M703343200

7 January 2021

Passing the baton in base excision repair

1 reference

https://api.crossref.org/works/10.1074/JBC.M703343200

7 January 2021

Werner syndrome cells escape hydrogen peroxide-induced cell proliferation arrest

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7 January 2021

Mucking with metabolism

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7 January 2021

Identifiers

DOI

10.1074/JBC.M703343200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611195 AND SRC:MED&resulttype=core&format=json

1 January 2020

1 reference