The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins (Q24315710)

1

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Paola Massimi

2

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Christel Navarro

3

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Jean-Paul Borg

4

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Lawrence Banks

Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry

5

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language of work or name

English

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publication date

15 September 2005

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published in

Oncogene

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volume

24

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issue

41

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page(s)

6222-30

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cites work

1 reference

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Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

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Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

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Integrated activity of PDZ protein complexes regulates epithelial polarity

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LAP proteins: what's up with epithelia?

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Differential expression of the human homologue of drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy

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MAGI-1 interacts with beta-catenin and is associated with cell-cell adhesion structures

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Identification of mNET1 as a candidate ligand for the first PDZ domain of MAGI-1

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hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

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Mutational analysis of the discs large tumour suppressor identifies domains responsible for human papillomavirus type 18 E6-mediated degradation

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Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

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Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins

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The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo

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Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

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Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

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Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

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Basolateral targeting by leucine-rich repeat domains in epithelial cells

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HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation

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Redistribution of the discs large tumor suppressor protein during mitosis

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Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

21 January 2018

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Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

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Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix

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Junctional recruitment of mammalian Scribble relies on E-cadherin engagement

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The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus

21 January 2018

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Chimaeric HPV E6 proteins allow dissection of the proteolytic pathways regulating different E6 cellular target proteins

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PDZ domains bind carboxy-terminal sequences of target proteins

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Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.

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HPV E6 and MAGUK protein interactions: determination of the molecular basis for specific protein recognition and degradation

21 January 2018

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Two polymorphic variants of wild-type p53 differ biochemically and biologically

21 January 2018

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Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation

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Functional expression of rat synapse-associated proteins SAP97 and SAP102 in Drosophila dlg-1 mutants: effects on tumor suppression and synaptic bouton structure.

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Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias

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Activity of the human papillomavirus E6 PDZ-binding motif correlates with an enhanced morphological transformation of immortalized human keratinocytes.

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Transformation of mammalian cells with genes from procaryotes and eucaryotes

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The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

21 January 2018

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Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

21 January 2018

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Human papillomaviruses in the pathogenesis of anogenital cancer

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HPV E6 targeted degradation of the discs large protein: evidence for the involvement of a novel ubiquitin ligase

21 January 2018

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inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1038/SJ.ONC.1208757

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1037595058

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Fatcat ID

release_bzhkwz42b5dfjnlxmkldu6lurm

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16103886

1 reference

Consolidated OpenCitations Corpus – April 2017