Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth (Q24315648)

negative regulation of cell population proliferation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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H Asao

1

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Y Sasaki

2

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T Arita

3

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N Tanaka

4

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K Endo

5

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H Kasai

6

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T Takeshita

7

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Y Endo

8

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T Fujita

9

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K Sugamura

Journal of Biological Chemistry

10

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language of work or name

English

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publication date

26 December 1997

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published in

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volume

272

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issue

52

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page(s)

32785-91

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Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

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Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction

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Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM

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Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain

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Hrs-2 is an ATPase implicated in calcium-regulated secretion

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STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction

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A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization

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Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

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Cloning of the gamma chain of the human IL-2 receptor

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Differential regulation of early response genes and cell proliferation through the human granulocyte macrophage colony-stimulating factor receptor: selective activation of the c-fos promoter by genistein

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The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations

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Regional localization of the gene for thyroid peroxidase to human chromosome 2p25 and mouse chromosome 12C

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inferred from DOI database lookup

7 January 2021

based on heuristic

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

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inferred from DOI database lookup

7 January 2021

based on heuristic

Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

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