Identification of the U-937 membrane-associated proteinase interacting with the V3 loop of HIV-1 gp120 as cathepsin G (Q24315636)

serine-type endopeptidase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

L E Avril

1

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M Di Martino-Ferrer

2

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G Pignede

3

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M Séman

4

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F Gauthier

Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells.

5

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language of work or name

English

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publication date

23 May 1994

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published in

FEBS Letters

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volume

345

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issue

1

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page(s)

81-6

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cites work

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The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

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Involvement of tryptase-related cellular protease(s) in human immunodeficiency virus type 1 infection

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Tryptase TL2in the membrane of human T4 lymphocytes is a novel binding protein of the V3 domain of HIV-1 envelope glycoprotein gp120

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Separation and partial characterization of proteinases with substrate specificity for basic amino acids from human MOLT-4 T lymphocytes: identification of those inhibited by variable-loop-V3 peptides of HIV-1 (human immunodeficiency virus-1) envelop

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A principal neutralizing domain of human immunodeficiency virus type 1 interacts with proteinase-like molecule(s) at the surface of Molt-4 clone 8 cells

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Interaction between a membrane-associated serine proteinase of U-937 monocytes and peptides from the V3 loop of the human immunodeficiency virus type 1 (HIV-1) gp120 envelope glycoprotein

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T cell activation antigen, CD26, as a cofactor for entry of HIV in CD4 cells

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Effect of mutations in the V3 loop of HIV-1 gp120 on infectivity and susceptibility to proteolytic cleavage

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Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

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Alteration of HIV-1 infectivity and neutralization by a single amino acid replacement in the V3 loop domain

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Tissue sulfhydryl groups

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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An immunochemical approach to investigating the mechanism of inhibition of cysteine proteinases by members of the cystatin superfamily.

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Molecular cloning of human cathepsin G: structural similarity to mast cell and cytotoxic T lymphocyte proteinases

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DNA sequencing with chain-terminating inhibitors

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How antibodies block HIV infection: paths to an AIDS vaccine

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A neutralizing epitope of human immunodeficiency virus type 1 has homologous amino acid sequences with the active site of inter-alpha-trypsin inhibitor

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A chink in HIV's armour?

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The role of the V3 loop of gp120 in HIV infection.

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A sensitive, coupled assay for plasminogen activator using a thiol ester substrate for plasmin

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The isoforms of human neutrophil elastase and cathepsin G differ in their carbohydrate side chain structures

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Inactivation of interleukin-6 in vitro by monoblastic U937 cell plasma membranes involves both protease and peptidyl-transferase activities

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The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: a possible function in viral fusion?

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inferred from DOI database lookup

7 January 2021

based on heuristic

Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells

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inferred from DOI database lookup

7 January 2021

based on heuristic

Cofactor requirement for human immunodeficiency virus type 1 entry into a CD4-expressing human cell line

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