HOXA5-twist interaction alters p53 homeostasis in breast cancer cells (Q24315091)

Twist family bHLH transcription factor 1

GOA release 2020-03-11

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transcription factor binding

GOA release 2020-03-11

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GOA release 2020-03-11

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Ioannis A Stasinopoulos

1

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Yelena Mironchik

2

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Ana Raman

3

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Flonne Wildes

4

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Paul Winnard

5

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Venu Raman

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

21 January 2005

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published in

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volume

280

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issue

3

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page(s)

2294-9

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cites work

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Conserved usage of gap and homeotic genes in patterning the CNS.

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Evolution of a transcriptional repression domain in an insect Hox protein

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Human HOX gene mutations

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Aberrant expression of homeobox gene HOXA7 is associated with müllerian-like differentiation of epithelial ovarian tumors and the generation of a specific autologous antibody response

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Compromised HOXA5 function can limit p53 expression in human breast tumours

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

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Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15)

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Homeobox genes in normal and malignant cells.

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twist: a myogenic switch in Drosophila.

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A Twist in fate: evolutionary comparison of Twist structure and function

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Genetic analysis of patients with the Saethre-Chotzen phenotype

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Saethre-Chotzen mutations cause TWIST protein degradation or impaired nuclear location

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Mutations in the human TWIST gene

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Mutations of the TWIST gene in the Saethre-Chotzen syndrome

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Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity

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Twist is a potential oncogene that inhibits apoptosis

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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

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Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A

21 January 2018

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The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter

21 January 2018

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Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family

21 January 2018

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The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation

21 January 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

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p21(WAF1) is associated with CDK2 and CDK4 protein during HL-60 cell differentiation by TPA treatment

21 January 2018

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p53-Mdm2--the affair that never ends

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ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

21 January 2018

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Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M411018200

Stress signals utilize multiple pathways to stabilize p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M411018200

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M411018200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411018200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

15545268

1 reference

Consolidated OpenCitations Corpus – April 2017