Gene from a psoriasis susceptibility locus primes the skin for inflammation (Q24314913)

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18 January 2020

title

Gene from a psoriasis susceptibility locus primes the skin for inflammation (English)

1 reference

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S100 calcium binding protein A7A

18 January 2020

main subject

inflammation

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protein self-association

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Chemokine (C-X-C motif) ligand 2

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Tumor necrosis factor

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Colony stimulating factor 2 (granulocyte-macrophage)

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Interleukin 23, alpha subunit p19

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Chemokine (C-C motif) ligand 5

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S100 calcium binding protein A7A

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Advanced glycosylation end product-specific receptor

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Interleukin 1 alpha

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4

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18 January 2020

Triantafyllos Chavakis

11

object named as

Triantafyllos Chavakis

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18 January 2020

12

Stuart H Yuspa

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18 January 2020

9

Ulrike Lichti

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18 January 2020

5

Christophe Cataisson

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18 January 2020

2

Francesca Mascia

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18 January 2020

10

Thomas Ruzicka

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18 January 2020

author name string

Ronald Wolf

1

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18 January 2020

Alif Dharamsi

3

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18 January 2020

Val Bliskovski

6

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18 January 2020

Jason Winston

7

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18 January 2020

Lionel Feigenbaum

8

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18 January 2020

language of work or name

English

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publication date

1 December 2010

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Science Translational Medicine

18 January 2020

published in

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18 January 2020

volume

2

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18 January 2020

issue

61

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18 January 2020

page(s)

61ra90

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A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

18 January 2020

cites work

1 reference

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Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

20 April 2017

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Intracellular and extracellular roles of S100 proteins

20 April 2017

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Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin

20 April 2017

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The mouse S100A15 ortholog parallels genomic organization, structure, gene expression, and protein-processing pattern of the human S100A7/A15 subfamily during epidermal maturation

20 April 2017

1 reference

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Highly homologous hS100A15 and hS100A7 proteins are distinctly expressed in normal breast tissue and breast cancer

20 April 2017

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Conditional gene expression in the epidermis of transgenic mice using the tetracycline-regulated transactivators tTA and rTA linked to the keratin 5 promoter

20 April 2017

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Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

20 April 2017

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

20 April 2017

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

20 April 2017

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Recombinantly engineered human proteins: transforming the treatment of psoriasis

20 April 2017

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Pathogenesis and clinical features of psoriasis

21 January 2018

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Pathogenesis and therapy of psoriasis

21 January 2018

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Immunopathogenic mechanisms in psoriasis.

21 January 2018

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Clearance of severe psoriasis after allogenic bone marrow transplantation

21 January 2018

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Dermal injection of immunocytes induces psoriasis

21 January 2018

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Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production.

21 January 2018

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Getting under the skin: the immunogenetics of psoriasis

21 January 2018

1 reference

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Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis

21 January 2018

1 reference

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Molecular dissection of psoriasis: integrating genetics and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3001108

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3001108

Evidence for differential S100 gene over-expression in psoriatic patients from genetically heterogeneous pedigrees

21 January 2018

1 reference

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Animal models of psoriasis - what can we learn from them?

21 January 2018

1 reference

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Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder

21 January 2018

1 reference

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Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis

21 January 2018

1 reference

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Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

21 January 2018

1 reference

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Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

21 January 2018

1 reference

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S100 proteins in the epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3001108

Molecular cloning and characterization of alternatively spliced mRNA isoforms from psoriatic skin encoding a novel member of the S100 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3001108

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3001108

Keratinocytes from patients with atopic dermatitis and psoriasis show a distinct chemokine production profile in response to T cell-derived cytokines

21 January 2018

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CXCR2 ligands and G-CSF mediate PKCalpha-induced intraepidermal inflammation

21 January 2018

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IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

21 January 2018

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Immunopathogenesis of psoriasis

21 January 2018

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RAGE signaling sustains inflammation and promotes tumor development

21 January 2018

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Epidemiology and the genetics of psoriasis

21 January 2018

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Genetic analysis of the epidermal differentiation complex (EDC) on human chromosome 1q21: chromosomal orientation, new markers, and a 6-Mb YAC contig

21 January 2018

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Psoriasis: dysregulation of innate immunity

21 January 2018

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Psoriasis: a T-cell-mediated autoimmune disease induced by streptococcal superantigens?

21 January 2018

1 reference

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The immunopathology of psoriasis

21 January 2018

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Injection of pre-psoriatic skin with CD4 T cells induces psoriasis

21 January 2018

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Mouse models of psoriasis.

21 January 2018

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A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin

21 January 2018

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Protein kinase C alpha-mediated chemotaxis of neutrophils requires NF-kappa B activity but is independent of TNF alpha signaling in mouse skin in vivo

21 January 2018

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Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment

21 January 2018

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The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment

21 January 2018

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The Cytokine Network in Lesional and Lesion-Free Psoriatic Skin Is Characterized by a T-Helper Type 1 Cell-Mediated Response

21 January 2018

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Keratinocytes regain momentum as instigators of cutaneous inflammation

21 January 2018

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12 December 2020

Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice

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12 December 2020

Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.

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12 December 2020

Targeting tumor necrosis factor alpha in psoriasis and psoriatic arthritis

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12 December 2020

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

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12 December 2020

Novel S100A7 (psoriasin)/S100A15 (koebnerisin) subfamily: highly homologous but distinct in regulation and function

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12 December 2020

The Koebner phenomenon

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12 December 2020

Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.

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12 December 2020

Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines.

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12 December 2020

Stratum corneum structure and function correlates with phenotype in psoriasis

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12 December 2020

Evidence that a locus for familial psoriasis maps to chromosome 4q

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12 December 2020

T-Lymphocyte Dependence of Psoriatic Pathology in Human Psoriatic Skin Grafted to SCID Mice

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12 December 2020

The genetics of psoriasis: a complex disorder of the skin and immune system

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12 December 2020

10.1126/SCITRANSLMED.3001108

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21148126 AND SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21148126 AND SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

21148126

1 reference