The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73 (Q24311644)

GOA release 2020-03-11

protein ubiquitination

1 reference

GOA release 2020-03-11

1

A Peschiaroli

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author name string

F Scialpi

2

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F Bernassola

3

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M Pagano

4

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G Melino

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

5

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language of work or name

English

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publication date

3 September 2009

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published in

Oncogene

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volume

28

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issue

35

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page(s)

3157-66

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cites work

1 reference

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Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation

19 March 2017

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FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activity

19 March 2017

1 reference

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SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

19 March 2017

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The ubiquitin-protein ligase Itch regulates p73 stability

19 March 2017

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The F-box protein family.

19 March 2017

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A family of mammalian F-box proteins

19 March 2017

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Identification of a family of human F-box proteins

19 March 2017

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p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

19 March 2017

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The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

19 March 2017

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Structural evolution of C-terminal domains in the p53 family

19 March 2017

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F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex

19 March 2017

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Function and regulation of cullin-RING ubiquitin ligases

19 March 2017

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S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

19 March 2017

1 reference

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The SCF ubiquitin ligase: insights into a molecular machine

19 March 2017

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Dual mode of degradation of Cdc25 A phosphatase

19 March 2017

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Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells

19 March 2017

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

19 March 2017

1 reference

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Covalent modification of all members of human cullin family proteins by NEDD8

19 March 2017

1 reference

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Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

19 March 2017

1 reference

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The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

19 March 2017

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Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

19 March 2017

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

7 April 2017

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Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

The HECT family of E3 ubiquitin ligases: multiple players in cancer development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

The impact of p53 and p73 on aneuploidy and cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Ubiquitin and ubiquitin-like modifications of the p53 family

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Adaptive evolution in two large families of ubiquitin-ligase adapters in nematodes and plants

27 September 2017

1 reference

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Experimental tests to definitively determine ubiquitylation of a substrate.

27 September 2017

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The ubiquitin system for protein degradation and some of its roles in the control of the cell-division cycle (Nobel lecture).

27 September 2017

1 reference

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p73 induces apoptosis by different mechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Ubiquitin-dependent degradation of p73 is inhibited by PML.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

p73, the "assistant" guardian of the genome?

27 September 2017

1 reference

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p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

deltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

p73: Friend or foe in tumorigenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Induction of neuronal differentiation by p73 in a neuroblastoma cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Structure, function and regulation of p63 and p73.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

Two new p73 splice variants, gamma and delta, with different transcriptional activity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

DNA damage induces the rapid and selective degradation of the DeltaNp73 isoform, allowing apoptosis to occur

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3865854

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

30 May 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.177

Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.177

The SCF FSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.177

Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.177

p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.177

p73-mediated transcriptional activity is negatively regulated by polo-like kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.177

Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants ε and ζ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.177

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.177