The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication (Q24310354)

Polo like kinase 4

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S-phase kinase associated protein 1

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F-box and WD repeat domain containing 5

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SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

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12

Pierre Gönczy

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Michael Manns

10

object named as

Michael P Manns

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author name string

Anja Puklowski

1

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Yahya Homsi

2

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Debora Keller

3

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Martin May

4

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Sangeeta Chauhan

5

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Uta Kossatz

6

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Viktor Grünwald

7

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Stefan Kubicka

8

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Andreas Pich

9

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Ingrid Hoffmann

11

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Nisar P Malek

Centrioles, centrosomes, and cilia in health and disease

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language of work or name

English

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publication date

August 2011

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published in

Nature Cell Biology

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volume

13

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issue

8

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page(s)

1004-9

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cites work

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A mechanism linking extra centrosomes to chromosomal instability

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WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase

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SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells

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Centriole assembly requires both centriolar and pericentriolar material proteins

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Mechanism limiting centrosome duplication to once per cell cycle

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"It takes two to tango": understanding how centrosome duplication is regulated throughout the cell cycle

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Plk4-induced centriole biogenesis in human cells

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Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

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The Polo kinase Plk4 functions in centriole duplication

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Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP.

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Control of centriole length by CPAP and CP110.

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Centriolar SAS-5 is required for centrosome duplication in C. elegans

21 January 2018

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CPAP is a cell-cycle regulated protein that controls centriole length

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Control of cell growth by the SCF and APC/C ubiquitin ligases

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Function and regulation of cullin-RING ubiquitin ligases

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Systematic analysis and nomenclature of mammalian F-box proteins

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

1 reference

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

21 January 2018

1 reference

Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels

21 January 2018

1 reference

The role of the destruction box and its neighbouring lysine residues in cyclin B for anaphase ubiquitin-dependent proteolysis in fission yeast: defining the D-box receptor

21 January 2018

1 reference

Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle

21 January 2018

1 reference

Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity

21 January 2018

1 reference

Autophosphorylation of polo-like kinase 4 and its role in centriole duplication

21 January 2018

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SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation

21 January 2018

1 reference

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

21 January 2018

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