The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling (Q24308827)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

title

The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

Sonic hedgehog signaling molecule

1 February 2020

main subject

1 reference

Hedgehog interacting protein

GOA release 2020-03-11

1 reference

negative regulation of signal transduction

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Suzie J Scales

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Ivan Bosanac

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

Henry R Maun

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

Xiaohui Wen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

Andreas Lingel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

J Fernando Bazan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

Frederic J de Sauvage

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

Sarah G Hymowitz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

Robert A Lazarus

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

language of work or name

English

0 references

publication date

28 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

1 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

691-697

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

Hedgehog signaling in animal development: paradigms and principles

1 February 2020

cites work

1 reference

Tissue repair and stem cell renewal in carcinogenesis

20 April 2017

1 reference

Autoproteolysis in hedgehog protein biogenesis

20 April 2017

1 reference

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

20 April 2017

1 reference

Cholesterol modification of hedgehog signaling proteins in animal development

20 April 2017

1 reference

Identification of a palmitic acid-modified form of human Sonic hedgehog

20 April 2017

1 reference

Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched

20 April 2017

1 reference

Dual roles for patched in sequestering and transducing Hedgehog

20 April 2017

1 reference

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

20 April 2017

1 reference

CDO: An Oncogene-, Serum-, and Anchorage-regulated Member of the Ig/Fibronectin Type III Repeat Family

20 April 2017

1 reference

Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly

20 April 2017

1 reference

BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation

20 April 2017

1 reference

The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice

20 April 2017

1 reference

The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development

20 April 2017

1 reference

The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla

20 April 2017

1 reference

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

20 April 2017

1 reference

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

20 April 2017

1 reference

Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors

20 April 2017

1 reference

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

20 April 2017

1 reference

Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair

20 April 2017

1 reference

Active-site structure of the soluble quinoprotein glucose dehydrogenase complexed with methylhydrazine: a covalent cofactor-inhibitor complex

20 April 2017

1 reference

A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog

20 April 2017

1 reference

Patched acts catalytically to suppress the activity of Smoothened

20 April 2017

1 reference

The structure of VanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance

20 April 2017

1 reference

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

20 April 2017

1 reference

Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor

20 April 2017

1 reference

Combined activities of hedgehog signaling inhibitors regulate pancreas development

20 April 2017

1 reference

Molecular screening of SHH, ZIC2, SIX3, and TGIF genes in patients with features of holoprosencephaly spectrum: Mutation review and genotype-phenotype correlations

20 April 2017

1 reference

Mutations in IHH, encoding Indian hedgehog, cause brachydactyly type A-1

20 April 2017

1 reference

A novel mutation in the IHH gene causes brachydactyly type A1: a 95-year-old mystery resolved

20 April 2017

1 reference

Identification of a mutation in the Indian Hedgehog (IHH) gene causing brachydactyly type A1 and evidence for a third locus

20 April 2017

1 reference

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

20 April 2017

1 reference

A small molecule that binds Hedgehog and blocks its signaling in human cells

20 April 2017

1 reference

Mapping sonic hedgehog-receptor interactions by steric interference

20 April 2017

1 reference

Characterization of two patched receptors for the vertebrate hedgehog protein family

20 April 2017

1 reference

Coot: model-building tools for molecular graphics

20 April 2017

1 reference

Likelihood-enhanced fast translation functions

20 April 2017

1 reference

Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0

20 April 2017

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Use of TLS parameters to model anisotropic displacements in macromolecular refinement

20 April 2017

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Hedgehog signaling in development and cancer.

20 April 2017

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

21 January 2018

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The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

21 January 2018

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Biochemical evidence that patched is the Hedgehog receptor

21 January 2018

1 reference

Patching the gaps in Hedgehog signalling

21 January 2018

1 reference

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

21 January 2018

1 reference

The ihog cell-surface proteins bind Hedgehog and mediate pathway activation

21 January 2018

1 reference

Structure of a heparin-dependent complex of Hedgehog and Ihog

21 January 2018

1 reference

Comparative biological responses to human Sonic, Indian, and Desert hedgehog

21 January 2018

1 reference

A paracrine requirement for hedgehog signalling in cancer

21 January 2018

1 reference

Structure and mechanism of soluble glucose dehydrogenase and other PQQ-dependent enzymes

21 January 2018

1 reference

Soluble aldose sugar dehydrogenase from Escherichia coli: a highly exposed active site conferring broad substrate specificity.

21 January 2018

1 reference

A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

21 January 2018

1 reference

Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

21 January 2018

1 reference

21 January 2018

1 reference

Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling

21 January 2018

1 reference

Answering a century old riddle: brachydactyly type A1.

21 January 2018

1 reference

A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range

21 January 2018

1 reference

Small-molecule modulators of Hh and Wnt signaling pathways

21 January 2018

1 reference

MEROPS: the peptidase database

21 January 2018

1 reference

A novel heterozygous mutation in the Indian hedgehog gene (IHH) is associated with brachydactyly type A1 in a Chinese family

31 March 2020

1 reference

Preconceptional ancestry-based carrier couple screening for cystic fibrosis and haemoglobinopathies: what determines the intention to participate or not and actual participation?

31 March 2020

1 reference

Processing of X-ray diffraction data collected in oscillation mode

31 March 2020

1 reference

Brachydactyly A-1 mutations restricted to the central region of the N-terminal active fragment of Indian Hedgehog

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19561609

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.1632

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

5102426

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561609 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 February 2020

1041793708

0 references

OpenCitations bibliographic resource ID

5102426

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

5102426

1 reference