Hydrophobic imbalance in the cytoplasmic domain of phospholamban is a determinant for lethal dilated cardiomyopathy (Q24307897)

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26 January 2020

title

Hydrophobic imbalance in the cytoplasmic domain of phospholamban is a determinant for lethal dilated cardiomyopathy (English)

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26 January 2020

0 references

1 reference

GOA release 2020-03-11

regulation of ATPase-coupled calcium transmembrane transporter activity

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GOA release 2020-03-11

hydrophobicity

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inferred from title

dilated cardiomyopathy

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2

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26 January 2020

author name string

Delaine K Ceholski

series ordinal

1

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26 January 2020

Howard S Young

series ordinal

3

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26 January 2020

language of work or name

English

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publication date

16 March 2012

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Journal of Biological Chemistry

26 January 2020

published in

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26 January 2020

volume

287

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26 January 2020

issue

20

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26 January 2020

page(s)

16521-16529

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427649 AND SRC:MED&resulttype=core&format=json

Effects of phospholamban transmembrane mutants on the calcium affinity, maximal activity, and cooperativity of the sarcoplasmic reticulum calcium pump

26 January 2020

cites work

1 reference

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A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.

19 March 2017

1 reference

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Modeling of the inhibitory interaction of phospholamban with the Ca2 ATPase.

19 March 2017

1 reference

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Comparable levels of Ca-ATPase inhibition by phospholamban in slow-twitch skeletal and cardiac sarcoplasmic reticulum

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Characterizing phospholamban to sarco(endo)plasmic reticulum Ca2 -ATPase 2a (SERCA2a) protein binding interactions in human cardiac sarcoplasmic reticulum vesicles using chemical cross-linking

19 March 2017

1 reference

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Activating and Deactivating Roles of Lipid Bilayers on the Ca2 -ATPase/Phospholamban Complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Phospholamban Binds with Differential Affinity to Calcium Pump Conformers

27 September 2017

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Targeted Gene Therapy for the Treatment of Heart Failure

27 September 2017

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Functional and physical competition between phospholamban and its mutants provides insight into the molecular mechanism of gene therapy for heart failure.

27 September 2017

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Lethal Arg9Cys phospholamban mutation hinders Ca 2 -ATPase regulation and phosphorylation by protein kinase A

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Phosphorylation and Mutation of Phospholamban Alter Physical Interactions With the Sarcoplasmic Reticulum Calcium Pump

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Relative affinity of calcium pump isoforms for phospholamban quantified by fluorescence resonance energy transfer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

The genetics of dilated cardiomyopathy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Ca2 binding to site I of the cardiac Ca2 pump is sufficient to dissociate phospholamban

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

A human phospholamban promoter polymorphism in dilated cardiomyopathy alters transcriptional regulation by glucocorticoids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Phosphorylation-dependent conformational switch in spin-labeled phospholamban bound to SERCA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Interactions between Ca2 -ATPase and the pentameric form of phospholamban in two-dimensional co-crystals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Phospholamban: a crucial regulator of cardiac contractility

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Locating phospholamban in co-crystals with Ca(2 )-ATPase by cryoelectron microscopy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Phospholamban inhibitory function is activated by depolymerization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Functional reconstitution of recombinant phospholamban with rabbit skeletal Ca(2 )-ATPase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Reconstitution of a calcium pump using defined membrane components

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Three-dimensional crystals of CaATPase from sarcoplasmic reticulum. Symmetry and molecular packing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Phospholamban: a regulatory protein of the cardiac sarcoplasmic reticulum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Amino acids Glu2 to Ile18 in the cytoplasmic domain of phospholamban are essential for functional association with the Ca(2 )-ATPase of sarcoplasmic reticulum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351288

Rapid, high-yield expression and purification of Ca2 -ATPase regulatory proteins for high-resolution structural studies

27 September 2017

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Co-reconstitution of phospholamban mutants with the Ca-ATPase reveals dependence of inhibitory function on phospholamban structure

30 May 2018

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Guidelines for membrane protein engineering derived from de novo designed model peptides

30 May 2018

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Comparative studies of cardiac and skeletal sarcoplasmic reticulum ATPases. Effect of a phospholamban antibody on enzyme activation by Ca2 .

30 May 2018

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Kinetic and equilibrium characterization of an energy-transducing enzyme and its partial reactions.

30 May 2018

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The effects of calcium, temperature and phospholamban phosphorylation on the dynamics of the calcium-stimulated ATPase of canine cardiac sarcoplasmic reticulum

30 May 2018

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Dependence of cardiac sarcoplasmic reticulum calcium pump activity on the phosphorylation status of phospholamban

30 May 2018

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PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: summary of the literature and implications for genetic testing.

30 May 2018

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Genetic deletion of arginine 14 in phospholamban causes dilated cardiomyopathy with attenuated electrocardiographic R amplitudes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M112.360859

The effects of mutation on the regulatory properties of phospholamban in co-reconstituted membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M112.360859

Molecular mechanisms of reduced sarcoplasmic reticulum Ca(2 ) uptake in human failing left ventricular myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M112.360859

Phospholamban remains associated with the Ca2 - and Mg2 -dependent ATPase following phosphorylation by cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M112.360859

Frequency and Phenotypes of Familial Dilated Cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M112.360859

Role of leucine 31 of phospholamban in structural and functional interactions with the Ca2 pump of cardiac sarcoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M112.360859

Nature and site of phospholamban regulation of the Ca2 pump of sarcoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M112.360859

Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2 )-ATPase in failing and nonfailing human myocardium

21 January 2018

1 reference

12 December 2020

Alterations of Sarcoplasmic Reticulum Proteins in Failing Human Dilated Cardiomyopathy

1 reference

12 December 2020

Purified, reconstituted cardiac Ca2 -ATPase is regulated by phospholamban but not by direct phosphorylation with Ca2 /calmodulin-dependent protein kinase

1 reference

12 December 2020

Phosphorylation of phospholamban by cAMP-dependent protein kinase enhances interactions between Ca-ATPase polypeptide chains in cardiac sarcoplasmic reticulum membranes

1 reference

12 December 2020

Effects of Ser16 phosphorylation on the allosteric transitions of phospholamban/Ca(2 )-ATPase complex

1 reference

12 December 2020

Phospholamban R14 deletion results in late-onset, mild, hereditary dilated cardiomyopathy

1 reference

12 December 2020

Mechanism of reversal of phospholamban inhibition of the cardiac Ca2 -ATPase by protein kinase A and by anti-phospholamban monoclonal antibody 2D12

1 reference

12 December 2020

Mutations in the human phospholamban gene in patients with heart failure

1 reference

12 December 2020

Maximal inhibition of SERCA2 Ca(2 ) affinity by phospholamban in transgenic hearts overexpressing a non-phosphorylatable form of phospholamban

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12 December 2020

Mutation of the phospholamban promoter associated with hypertrophic cardiomyopathy

1 reference

12 December 2020

Phospholipid orientation in sarcoplasmic membranes: spin-label ESR and proton MNR studies

1 reference

12 December 2020

Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains

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12 December 2020

Phospholamban stoichiometry in canine cardiac muscle sarcoplasmic reticulum

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12 December 2020

Identifiers

DOI

10.1074/JBC.M112.360859

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427649 AND SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427649 AND SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

22427649

1 reference