Src-family kinases in B-cell development and signaling (Q24307580)

LYN proto-oncogene, Src family tyrosine kinase

Europe PubMed Central

title

Src-family kinases in B-cell development and signaling (English)

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main subject

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negative regulation of immune response

GOA release 2020-03-11

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Differential effects of filipin and methyl-beta-cyclodextrin on B cell receptor signaling

GOA release 2020-03-11

author name string

Stephen B Gauld

series ordinal

1

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John C Cambier

series ordinal

2

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language of work or name

English

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publication date

18 October 2004

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published in

Oncogene

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volume

23

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issue

48

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page(s)

8001-6

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cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Qualitative Regulation of B Cell Antigen Receptor Signaling by CD19: Selective Requirement for PI3-Kinase Activation, Inositol-1,4,5-Trisphosphate Production and Ca2 Mobilization

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL)

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Signal transduction by the B cell antigen receptor and its coreceptors

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https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

CD19 regulates intrinsic B lymphocyte signal transduction and activation through a novel mechanism of processive amplification

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

CD19 amplification of B lymphocyte Ca2 responses: a role for Lyn sequestration in extinguishing negative regulation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

The immunological synapse balances T cell receptor signaling and degradation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

T cell receptor signaling precedes immunological synapse formation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

A double-edged kinase Lyn: a positive and negative regulator for antigen receptor-mediated signals

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Distinct p53/56lyn and p59fyn domains associate with nonphosphorylated and phosphorylated Ig-alpha

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Myristylation and palmitylation of Src family members: the fats of the matter

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

CD19 Is a Substrate of the Antigen Receptor-Associated Protein Tyrosine Kinase in Human B Cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Dynamic regulation of Src-family kinases by CD45 in B cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Inhibition of the B cell by CD22: a requirement for Lyn

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Cutting edge: B cell antigen receptor signaling occurs outside lipid rafts in immature B cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

CD19 of B Cells as a Surrogate Kinase Insert Region to Bind Phosphatidylinositol 3-Kinase

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in lyn-/- mice

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Evidence for a preformed transducer complex organized by the B cell antigen receptor

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021

CD45 modulates phosphorylation of both autophosphorylation and negative regulatory tyrosines of Lyn in B cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208075

7 January 2021