NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest (Q24306490)

Gene Ontology release 2020-05-02

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1995004

inosine-diphosphatase activity

1 reference

Gene Ontology release 2020-05-02

1 reference

GOA release 2020-03-11

positive regulation of double-strand break repair

1 reference

Nudix (nucleoside diphosphate linked moiety X)-type motif 16

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Teruaki Iyama

1

0 references

Nona Abolhassani

2

0 references

Daisuke Tsuchimoto

3

0 references

Mari Nonaka

4

0 references

Yusaku Nakabeppu

Creative Commons Attribution-NonCommercial 2.5 Generic

5

0 references

language of work or name

English

0 references

publication date

August 2010

0 references

published in

Nucleic Acids Research

0 references

volume

38

0 references

issue

14

0 references

page(s)

4834-43

0 references

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Identification and biochemical characterization of a novel transcription elongation factor, Elongin A3

19 March 2017

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Inosine di- and triphosphate synthesis in erythrocytes and cell extracts

19 March 2017

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Mouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine

19 March 2017

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Incision at hypoxanthine residues in DNA by a mammalian homologue of the Escherichia coli antimutator enzyme endonuclease V

19 March 2017

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19 March 2017

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27 September 2017

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Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs.

27 September 2017

1 reference

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Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis.

27 September 2017

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MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides

27 September 2017

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Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids.

27 September 2017

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency in the Japanese population

27 September 2017

1 reference

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Mutation in the ITPA gene predicts intolerance to azathioprine

27 September 2017

1 reference

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Dynamics and diversions in base excision DNA repair of oxidized abasic lesions

27 September 2017

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RNA editing by adenosine deaminases generates RNA and protein diversity

27 September 2017

1 reference

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

27 September 2017

1 reference

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Interactions of the human, rat, Saccharomyces cerevisiae and Escherichia coli 3-methyladenine-DNA glycosylases with DNA containing dIMP residues

27 September 2017

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Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA

27 September 2017

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27 September 2017

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Lethality of a dut (deoxyuridine triphosphatase) mutation in Escherichia coli

27 September 2017

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DNA damage and mutation in human cells exposed to nitric oxide in vitro

27 September 2017

1 reference

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Removal of deoxyinosine from the Escherichia coli chromosome as studied by oligonucleotide transformation

27 September 2017

1 reference

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A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Antibody against Single-Stranded DNA Useful for Detecting Apoptotic Cells Recognizes Hexadeoxynucleotides with Various Base Sequences

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Antibody against single-stranded DNA detects both programmed cell death and drug-induced apoptosis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

ITPase-deficient mice show growth retardation and die before weaning.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Characterization of the structure and expression of mouse Itpa gene and its related sequences in the mouse genome.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Kinetics of muscle contraction and actomyosin NTP hydrolysis from rabbit using a series of metal-nucleotide substrates

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

RdgB acts to avoid chromosome fragmentation in Escherichia coli

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

The Nudix hydrolases of Deinococcus radiodurans.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Endonuclease V protects Escherichia coli against specific mutations caused by nitrous acid.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919730

Adenine nucleotide metabolism in relation to purine enzymes in liver, erythrocytes and cultured fibroblasts

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20385596

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKQ249

1 reference

1 reference

1 reference

PubMed publication ID

20385596

1 reference