Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive (Q24306328)

MTOR associated protein, LST8 homolog

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Ras homolog family member A

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Rac family small GTPase 1

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mechanistic target of rapamycin kinase

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RPTOR independent companion of MTOR complex 2

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regulation of actin cytoskeleton organization

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Paxillin

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FK506 binding protein 1a

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MTOR associated protein, LST8 homolog (S. cerevisiae)

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Mechanistic target of rapamycin kinase

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Ras homolog family member A

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Rac family small GTPase 1

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RPTOR independent companion of MTOR, complex 2

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Regulatory-associated protein of mTOR

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2

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Estela Jacinto

object named as

Estela Jacinto

1

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author name string

Anja Schmidt

3

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Shuo Lin

4

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Markus A Rüegg

5

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Alan Hall

6

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Michael N Hall

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

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language of work or name

English

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publication date

November 2004

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published in

Nature Cell Biology

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volume

6

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issue

11

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page(s)

1122-8

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cites work

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Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae

20 April 2017

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Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

20 April 2017

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

20 April 2017

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GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

20 April 2017

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Rho GTPases in cell biology

20 April 2017

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Mammalian target of rapamycin and protein kinase A signaling mediate the cardiac transcriptional response to glutamine

20 April 2017

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The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

20 April 2017

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The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.

20 April 2017

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Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function

20 April 2017

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

20 April 2017

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

20 April 2017

1 reference

A system for stable expression of short interfering RNAs in mammalian cells

20 April 2017

1 reference

T-Coffee: A novel method for fast and accurate multiple sequence alignment

20 April 2017

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Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

20 April 2017

1 reference

Tor signalling in bugs, brain and brawn

20 April 2017

1 reference

7 January 2021

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

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7 January 2021

Growth factor-induced actin reorganization in Swiss 3T3 cells

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7 January 2021

Paxillin: a focal adhesion-associated adaptor protein

1 reference

7 January 2021

Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration

1 reference

7 January 2021

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

7 January 2021

PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.

1 reference

7 January 2021

FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

1 reference

7 January 2021

Mammalian CAP interacts with CAP, CAP2, and actin

1 reference

7 January 2021

Mammalian TOR: a homeostatic ATP sensor

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7 January 2021

Determination of GTP loading on Rac and Cdc42 in platelets and fibroblasts

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7 January 2021