Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2 (Q24305114)

OPA1 mitochondrial dynamin like GTPase

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Prohibitin

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Voltage dependent anion channel 1

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Prohibitin 2

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protein stabilization

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Journal of Biological Chemistry

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Katsumi Kasashima

1

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Eriko Ohta

series ordinal

2

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Yasuo Kagawa

series ordinal

3

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Hitoshi Endo

series ordinal

4

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language of work or name

English

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publication date

24 November 2006

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published in

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volume

281

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issue

47

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page(s)

36401-10

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cites work

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Regulation of mitochondrial respiratory chain structure and function by estrogens/estrogen receptors and potential physiological/pathophysiological implications

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Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria

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Mitochondrial intermembrane proteins in cell death

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The prohibitin family of mitochondrial proteins regulate replicative lifespan

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

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Characterization of the plant homologue of prohibitin, a gene associated with antiproliferative activity in mammalian cells

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Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space

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Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function

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Differential regulation of Rb family proteins and prohibitin during camptothecin-induced apoptosis

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Androgens target prohibitin to regulate proliferation of prostate cancer cells.

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Structural organization of mitochondrial human complex I: role of the ND4 and ND5 mitochondria-encoded subunits and interaction with prohibitin

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The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells

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HAX-1, identified by differential display reverse transcription polymerase chain reaction, is overexpressed in lesional psoriasis

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An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

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Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

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Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA.

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The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans

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Prohibitin Induces the Transcriptional Activity of p53 and Is Exported from the Nucleus upon Apoptotic Signaling

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Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.

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Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals

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Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria

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