Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1 (Q24304774)

2

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M G Myers

3

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M Miralpeix

4

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M F White

Molecular and Cellular Biology

5

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language of work or name

English

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publication date

December 1993

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published in

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volume

13

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issue

12

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page(s)

7418-28

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cites work

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Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

19 March 2017

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Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

19 March 2017

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Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

19 March 2017

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Human skeletal muscle insulin receptor substrate-1. Characterization of the cDNA, gene, and chromosomal localization

19 March 2017

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The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp

19 March 2017

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

19 March 2017

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Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

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Oncogenes and signal transduction

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

7 April 2017

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Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

7 April 2017

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A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

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Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase

27 September 2017

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The new elements of insulin signaling. Insulin receptor substrate-1 and proteins with SH2 domains

27 September 2017

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Phosphorylation of the insulin receptor substrate IRS-1 by casein kinase II.

27 September 2017

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Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes

27 September 2017

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Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells.

27 September 2017

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Regulation of gene expression by insulin

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364813

How Cells Absorb Glucose / Gustav E. Lienhard, Jan W. Slot, David E. James and Mike M. Mueckler. - (1992)

27 September 2017

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Growth-regulated signal transduction by the MAP kinases and RSKs

27 September 2017

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Molecular physiology and genetics of NIDDM. Importance of metabolic staging

27 September 2017

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IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

27 September 2017

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YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364813

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364813

SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

30 May 2018

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Expression and function of IRS-1 in insulin signal transmission.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364813

The association of insulin-elicited phosphotyrosine proteins with src homology 2 domains

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364813

Regulation of the expression of pp160, a putative insulin receptor signal protein, by insulin, dexamethasone, and 1-methyl-3-isobutylxanthine in 3T3-L1 adipocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364813

Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells

30 May 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7504175

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7504175

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A manual sequencing method for identification of phosphorylated amino acids in phosphopeptides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7504175