Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction (Q24302344)

Calmodulin-1

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positive regulation of ryanodine-sensitive calcium-release channel activity

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Ryanodine receptor 2, cardiac

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author name string

Xiaojuan Xu

1

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Masafumi Yano

2

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Hitoshi Uchinoumi

3

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Akihiro Hino

4

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Takeshi Suetomi

5

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Makoto Ono

6

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Hiroki Tateishi

7

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Tetsuro Oda

8

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Shinichi Okuda

9

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Masahiro Doi

10

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Shigeki Kobayashi

11

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Takeshi Yamamoto

12

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Yasuhiro Ikeda

13

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Noriaki Ikemoto

14

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Masunori Matsuzaki

Biochemical and Biophysical Research Communications

15

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language of work or name

English

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publication date

9 April 2010

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published in

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volume

394

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issue

3

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page(s)

660-6

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cites work

Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death

1 reference

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Blocking the Ca2 -induced conformational transitions in calmodulin with disulfide bonds

19 March 2017

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Disruption of calcium homeostasis and arrhythmogenesis induced by mutations in the cardiac ryanodine receptor and calsequestrin

19 March 2017

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Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel

19 March 2017

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SparkMaster: automated calcium spark analysis with ImageJ

19 March 2017

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Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor.

19 March 2017

1 reference

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Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor.

27 September 2017

1 reference

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Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor

27 September 2017

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Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor

27 September 2017

1 reference

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Mechanisms of Disease: ryanodine receptor defects in heart failure and fatal arrhythmia.

27 September 2017

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Localization of a disease-associated mutation site in the three-dimensional structure of the cardiac muscle ryanodine receptor

27 September 2017

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Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure

27 September 2017

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Macromolecular complexes regulating cardiac ryanodine receptor function.

27 September 2017

1 reference

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Regulation of calcium release by interdomain interaction within ryanodine receptors

27 September 2017

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Apocalmodulin and Ca2 -calmodulin bind to neighboring locations on the ryanodine receptor

27 September 2017

1 reference

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Identification of target domains of the cardiac ryanodine receptor to correct channel disorder in failing hearts

30 May 2018

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Molecular Basis of Calmodulin Binding to Cardiac Muscle Ca2 Release Channel (Ryanodine Receptor)

29 November 2018

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Peptide probe study of the critical regulatory domain of the cardiac ryanodine receptor

29 November 2018

1 reference

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Culture and adenoviral infection of adult mouse cardiac myocytes: methods for cellular genetic physiology

29 November 2018

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PubMed

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