The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2 (Q24301411)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2	scientific article

Statements

scholarly article

0 references

The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2 (English)

0 references

Proprotein convertase subtilisin/kexin type 9

1 reference

GOA release 2020-03-11

very-low-density lipoprotein particle receptor binding

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

4

0 references

object named as

Annik Prat

9

0 references

object named as

Nabil G Seidah

10

0 references

author name string

Steve Poirier

1

0 references

Gaetan Mayer

2

0 references

Suzanne Benjannet

3

0 references

Jadwiga Marcinkiewicz

5

0 references

Nasha Nassoury

6

0 references

Harald Mayer

7

0 references

Johannes Nimpf

8

0 references

language of work or name

0 references

publication date

25 January 2008

0 references

Journal of Biological Chemistry

0 references

283

0 references

4

0 references

2363-72

0 references

Biomedicine. Lowering LDL--not only how low, but how long?

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The proprotein convertases and their implication in sterol and/or lipid metabolism

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Molecular biology of PCSK9: its role in LDL metabolism

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene: long-term follow-up and treatment response

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The LDL receptor gene family: signaling functions during development.

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Multiple sequence alignment with hierarchical clustering

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signaling

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Receptor clustering is involved in Reelin signaling

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Down-regulation of alpha v/beta 3 integrin via misrouting to lysosomes by overexpression of a beta 3Lamp1 fusion protein

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

LIS1-no more no less

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The proprotein convertases are potential targets in the treatment of dyslipidemia

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Selective expression of LDLR and VLDLR in myelinating oligodendrocytes

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Modulation of lipoprotein receptor functions by intracellular adaptor proteins

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

The C679X mutation in PCSK9 is present and lowers blood cholesterol in a Southern African population

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

21 January 2018

Nerve growth factor and proprotein convertases furin and PC7 in transected sciatic nerves and in nerve segments cultured in conditioned media: their presence in Schwann cells, macrophages, and smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

7 January 2021

based on heuristic

inferred from DOI database lookup

Complementation of mutations in the LDL pathway of receptor-mediated endocytosis by cocultivation of LDL receptor-defective hamster cell mutants

1 reference

https://api.crossref.org/works/10.1074/JBC.M708098200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q24301411&oldid=1634491314"