The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS (Q24300720)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

title

The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

main subject

Cell division cycle 73

1 reference

PAF1 homolog, Paf1/RNA polymerase II complex component

1 reference

CTR9 homolog, Paf1/RNA polymerase II complex component

1 reference

LEO1 homolog, Paf1/RNA polymerase II complex component

1 reference

RTF1 homolog, Paf1/RNA polymerase II complex component

1 reference

WD repeat domain 61

1 reference

positive regulation of transcription by RNA polymerase II

1 reference

author

Jaehoon Kim

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Mohamed Guermah

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

Robert G Roeder

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

1 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

volume

140

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

491-503

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells

18 January 2020

cites work

1 reference

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A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

19 March 2017

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The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors

19 March 2017

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Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo

19 March 2017

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The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions

19 March 2017

1 reference

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The human PAF complex coordinates transcription with events downstream of RNA synthesis

19 March 2017

1 reference

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The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II

19 March 2017

1 reference

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The parafibromin tumor suppressor protein is part of a human Paf1 complex

19 March 2017

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The role of chromatin during transcription

19 March 2017

1 reference

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

19 March 2017

1 reference

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Rtf1 is a multifunctional component of the Paf1 complex that regulates gene expression by directing cotranscriptional histone modification

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II.

19 March 2017

1 reference

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A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Histone H2B ubiquitylation is associated with elongating RNA polymerase II

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

The Paf1 complex has functions independent of actively transcribing RNA polymerase II.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Molecular evidence indicating that the yeast PAF complex is required for transcription elongation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

A highly purified RNA polymerase II elongation control system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

FACT, a Factor that Facilitates Transcript Elongation through Nucleosomes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice

19 March 2017

1 reference

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hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions

19 March 2017

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Elongation by RNA polymerase II: the short and long of it

19 March 2017

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Human RNA polymerase II-associated factor complex: dysregulation in cancer.

7 April 2017

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Drosophila Rtf1 functions in histone methylation, gene expression, and Notch signaling

27 September 2017

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Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program

27 September 2017

1 reference

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Drosophila Paf1 modulates chromatin structure at actively transcribed genes.

27 September 2017

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H2B ubiquitylation: the end is in sight

27 September 2017

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Running with RNA polymerase: eukaryotic transcript elongation

27 September 2017

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Synthetic lethal interactions suggest a role for the Saccharomyces cerevisiae Rtf1 protein in transcription elongation

27 September 2017

1 reference

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Identification of RTF1, a novel gene important for TATA site selection by TATA box-binding protein in Saccharomyces cerevisiae

27 September 2017

1 reference

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Paf1p, an RNA polymerase II-associated factor in Saccharomyces cerevisiae, may have both positive and negative roles in transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853908

Nucleosome loss activates yeast downstream promoters in vivo

27 September 2017

1 reference

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The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII

30 May 2018

1 reference

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RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit

30 May 2018

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Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism

29 November 2018

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The presence of nucleosomes on a DNA template prevents initiation by RNA polymerase II in vitro

29 November 2018

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12 December 2020

Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II

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12 December 2020

Nature of the nucleosomal barrier to RNA polymerase II

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12 December 2020

Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates

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12 December 2020

Nucleosomes can form a polar barrier to transcript elongation by RNA polymerase II

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12 December 2020

Purification of DNA-dependent RNA polymerase II from Saccharomyces cerevisiae

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7 January 2021

Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53

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7 January 2021

CDK8 is a stimulus-specific positive coregulator of p53 target genes

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7 January 2021

Transcription of in vitro assembled chromatin templates in a highly purified RNA polymerase II system

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7 January 2021

Isolation and functional characterization of the TRAP/mediator complex

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7 January 2021

Reconstitution and transcriptional analysis of chromatin in vitro

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7 January 2021

Activator-dependent transcription by mammalian RNA polymerase II: in vitro reconstitution with general transcription factors and cofactors

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7 January 2021

Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300.

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7 January 2021

The regulatory role for the ERCC3 helicase of general transcription factor TFIIH during promoter escape in transcriptional activation

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7 January 2021

ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly

1 reference

https://api.crossref.org/works/10.1016/J.CELL.2009.12.050

7 January 2021

Positive and negative TAF(II) functions that suggest a dynamic TFIID structure and elicit synergy with traps in activator-induced transcription

1 reference

https://api.crossref.org/works/10.1016/J.CELL.2009.12.050

7 January 2021

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Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20178742 AND SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

20178742

2 references