Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans (Q24300477)

GOA release 2020-03-11

syndecan binding

1 reference

heparan sulfate proteoglycans

GOA release 2020-03-11

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9

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Flonia Levy-Adam

6

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Neta Ilan

10

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Svetlana Gingis-Velitski

1

Svetlana Gingis-Velitski

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Anna Zetser

2

Anna Zetser

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Victoria Kaplan

3

Victoria Kaplan

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Yulia Bashenko

7

Yulia Bashenko

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Moshe Y Flugelman

8

Moshe Y Flugelman

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author name string

Olga Ben-Zaken

4

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Esti Cohen

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

15 October 2004

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published in

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volume

279

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issue

42

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page(s)

44084-92

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Heterodimer formation is essential for heparanase enzymatic activity

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Heparanase, a potential regulator of cell-matrix interactions

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Heparan sulfate proteoglycan as a plasma membrane carrier

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Heparanase expression in hepatocellular carcinoma and the cirrhotic liver

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Inflammatory cytokines and fatty acids regulate endothelial cell heparanase expression

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Endogenously expressed apolipoprotein E has different effects on cell lipid metabolism as compared to exogenous apolipoprotein E carried on triglyceride-rich particles

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Heparanase expression is a prognostic indicator for postoperative survival in pancreatic adenocarcinoma

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Trans-activation of heparanase promoter by ETS transcription factors

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Role of promoter methylation in regulation of the mammalian heparanase gene

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Mammary gland development requires syndecan-1 to create a beta-catenin/TCF-responsive mammary epithelial subpopulation

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Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling

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Biochemical characterization of the active heterodimer form of human heparanase (Hpa1) protein expressed in insect cells

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Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis

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Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers

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Regulation of Inducible Heparanase Gene Transcription in Activated T Cells by Early Growth Response 1

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Heparanase induces endothelial cell migration via protein kinase B/Akt activation

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Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism

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Lipoprotein lipase-mediated selective uptake from low density lipoprotein requires cell surface proteoglycans and is independent of scavenger receptor class B type 1

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Heparanase as mediator of angiogenesis: mode of action

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Syndecans in inflammation

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Cell-surface heparan sulfate proteoglycans: dynamic molecules mediating ligand catabolism.

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Functions of cell surface heparan sulfate proteoglycans

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Order out of chaos: assembly of ligand binding sites in heparan sulfate

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