TRIM5 is an innate immune sensor for the retrovirus capsid lattice (Q24300173)

Ubiquitin conjugating enzyme E2 N

1 reference

Tripartite motif containing 5

1 reference

protein K63-linked ubiquitination

1 reference

author

Thomas Pertel

Caterina Strambio-De-Castillia

1

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Caterina Strambio-De-Castillia

13

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Jeremy Luban

Jeremy Luban

17

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Walther Mothes

14

Walther Mothes

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Massimo Pizzato

15

Massimo Pizzato

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author name string

Stéphane Hausmann

2

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Damien Morger

3

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Sara Züger

4

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Jessica Guerra

5

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Josefina Lascano

6

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Christian Reinhard

7

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Federico A Santoni

8

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Pradeep D Uchil

9

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Laurence Chatel

10

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Aurélie Bisiaux

11

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Matthew L Albert

12

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Markus G Grütter

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

16

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language of work or name

English

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publication date

21 April 2011

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published in

Nature

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volume

472

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issue

7343

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page(s)

361-5

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Direct activation of protein kinases by unanchored polyubiquitin chains

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

TRIM5alpha selectively binds a restriction-sensitive retroviral capsid

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Atomic-level modelling of the HIV capsid

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Structural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

X-ray structures of the hexameric building block of the HIV capsid

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

An Atomic Model of the Interferon-β Enhanceosome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Hexagonal assembly of a restricting TRIM5alpha protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunodeficiency virus type 1 replication.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Host innate immune receptors and beyond: making sense of microbial infections

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Complex determinants within the Moloney murine leukemia virus capsid modulate susceptibility of the virus to Fv1 and Ref1-mediated restriction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Integration of murine leukemia virus DNA depends on mitosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Interferons and bacterial lipopolysaccharide protect macrophages from productive infection by human immunodeficiency virus in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081621

Assembly and analysis of conical models for the HIV-1 core.

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1038/NATURE09976

HIV immunology needs a new direction

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21512573

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE09976

1 reference

Dimensions Publication ID

1021413965

0 references

1 reference

1 reference

PubMed publication ID

21512573

1 reference