5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia (Q24299992)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23027611 AND SRC:MED&resulttype=core&format=json

9 March 2020

title

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia (English)

1 reference

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5-hydroxytryptamine receptor 6

9 March 2020

main subject

schizophrenia

0 references

1 reference

positive regulation of TOR signaling

1 reference

Mechanistic target of rapamycin kinase

1 reference

5-hydroxytryptamine (serotonin) receptor 6

1 reference

author

Séverine Chaumont-Dubel

2

1 reference

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9 March 2020

Martial Sévéno

7

1 reference

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9 March 2020

Kevin Fone

12

1 reference

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9 March 2020

13

Joël Bockaert

1 reference

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9 March 2020

author name string

Julie Meffre

1

1 reference

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9 March 2020

Clotilde Mannoury la Cour

3

1 reference

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9 March 2020

Florence Loiseau

4

1 reference

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9 March 2020

David J G Watson

5

1 reference

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9 March 2020

Anne Dekeyne

6

1 reference

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9 March 2020

Jean-Michel Rivet

8

1 reference

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9 March 2020

Florence Gaven

9

1 reference

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9 March 2020

Paul Déléris

10

1 reference

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9 March 2020

Denis Hervé

11

1 reference

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9 March 2020

Mark J Millan

14

1 reference

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9 March 2020

Philippe Marin

15

1 reference

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9 March 2020

language of work or name

English

0 references

publication date

1 October 2012

1 reference

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9 March 2020

published in

EMBO Molecular Medicine

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9 March 2020

volume

4

1 reference

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9 March 2020

issue

10

1 reference

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9 March 2020

page(s)

1043-1056

1 reference

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mTOR signaling in growth control and disease

9 March 2020

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1 reference

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Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat

19 March 2017

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Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

19 March 2017

1 reference

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

19 March 2017

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Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

19 March 2017

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Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

19 March 2017

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Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

19 March 2017

1 reference

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

19 March 2017

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19 March 2017

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Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

7 April 2017

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Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.

27 September 2017

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Mutations causing syndromic autism define an axis of synaptic pathophysiology

27 September 2017

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Animal models of schizophrenia.

27 September 2017

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Influence of social isolation in the rat on serotonergic function and memory--relevance to models of schizophrenia and the role of 5-HT₆ receptors

27 September 2017

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Blockade of dopamine D3 but not D2 receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment

27 September 2017

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5-HT(6) receptor and cognition.

27 September 2017

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mTORC1 signaling: what we still don't know

27 September 2017

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Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders

27 September 2017

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Huntington's disease is a disorder of the corpus striatum: focus on Rhes (Ras homologue enriched in the striatum)

27 September 2017

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5-HT6 receptor antagonists: prospects for the treatment of cognitive disorders including dementia.

27 September 2017

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27 September 2017

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27 September 2017

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Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex

27 September 2017

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Role of mTOR in physiology and pathology of the nervous system

27 September 2017

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Neuroplasticity of neocortical circuits in schizophrenia.

27 September 2017

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27 September 2017

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27 September 2017

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SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.

27 September 2017

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5-HT6 receptors: a novel target for cognitive enhancement

27 September 2017

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27 September 2017

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Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.

27 September 2017

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5-HT6 receptor antagonists enhance retention of a water maze task in the rat.

27 September 2017

1 reference

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A role for 5-ht6 receptors in retention of spatial learning in the Morris water maze.

27 September 2017

1 reference

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Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine

27 September 2017

1 reference

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Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002/EMMM.201201410

21 January 2018

Identifiers

DOI

10.1002/EMMM.201201410

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23027611 AND SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23027611 AND SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23027611

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23027611 AND SRC:MED&resulttype=core&format=json