Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity (Q24299668)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

title

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

T-box transcription factor T

18 January 2020

main subject

1 reference

Mix paired-like homeobox

1 reference

positive regulation of transcription by RNA polymerase II

1 reference

Mix1 homeobox-like 1 (Xenopus laevis)

1 reference

T-box 6

1 reference

T-box 3

1 reference

Eomesodermin

1 reference

Brachyury, T-box transcription factor T

1 reference

Goosecoid homeobox

1 reference

T-box 20

1 reference

author

Sue Mei Lim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

Andrew Elefanty

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

5

Edouard G Stanley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Lloyd A Pereira

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

Michael S Wong

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

Alexandra Sides

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

2 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

issue

12

1 reference

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18 January 2020

page(s)

e28394

1 reference

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Creative Commons Attribution 4.0 International

18 January 2020

copyright license

start time

2 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation

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Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

19 March 2017

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Eomesodermin is required for mouse trophoblast development and mesoderm formation

19 March 2017

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The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation

19 March 2017

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The T protein encoded by Brachyury is a tissue-specific transcription factor

19 March 2017

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Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells

19 March 2017

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Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

19 March 2017

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Sequential allocation and global pattern of movement of the definitive endoderm in the mouse embryo during gastrulation

19 March 2017

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Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor

19 March 2017

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Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos

19 March 2017

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Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo

19 March 2017

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Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein

19 March 2017

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The Brachyury gene encodes a novel DNA binding protein

19 March 2017

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Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells.

19 March 2017

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pEF-BOS, a powerful mammalian expression vector

7 April 2017

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Expression pattern of the mouse T gene and its role in mesoderm formation

7 April 2017

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Teasing out T-box targets in early mesoderm

7 April 2017

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Classical nuclear localization signals: definition, function, and interaction with importin alpha

27 September 2017

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Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene.

27 September 2017

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Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

27 September 2017

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The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells

27 September 2017

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Pax6 interacts with cVax and Tbx5 to establish the dorsoventral boundary of the developing eye.

27 September 2017

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T-box genes in early embryogenesis

27 September 2017

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Structure, upstream promoter region, and functional domains of a mouse and human Mix paired-like homeobox gene.

27 September 2017

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Gene targeting in a centralized facility

27 September 2017

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Cloning, expression analysis, and chromosomal localization of murine and human homologues of a Xenopus mix gene

27 September 2017

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The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

TheXenopus Brachyurypromoter is activated by FGF and low concentrations ofactivinandsuppressed by high concentrationsof activin and by paired-type homeodomain proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Cooperative dimerization of paired class homeo domains on DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Rapid activation by interferon alpha of a latent DNA-binding protein present in the cytoplasm of untreated cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Gastrulation in the mouse: the role of the homeobox gene goosecoid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Mapping and expression analysis of the mouse ortholog of Xenopus Eomesodermin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Goosecoid and mix.1 repress Brachyury expression and are required for head formation in Xenopus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Eomesodermin, a key early gene in Xenopus mesoderm differentiation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

A cell autonomous function of Brachyury in T/T embryonic stem cell chimaeras

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors.

30 May 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0028394

Mml, a mouse Mix-like gene expressed in the primitive streak

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0028394

Expression of T Protein in the Primitive Streak Is Necessary and Sufficient for Posterior Mesoderm Movement and Somite Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0028394

Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0028394

Mixl1 and oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0028394

Bowline mediates association of the transcriptional corepressor XGrg-4 with Tbx6 during somitogenesis in Xenopus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0028394

Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0028394

Determinants of T box protein specificity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Bix4 is activated directly by VegT and mediates endoderm formation in Xenopus development

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

A role for the vegetally expressed Xenopus gene Mix.1 in endoderm formation and in the restriction of mesoderm to the marginal zone

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

Chimeric analysis of T (Brachyury) gene function.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229578

BMP-4-responsive regulation of dorsal–ventral patterning by the homeobox protein Mix.1

29 November 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0028394

10.1371/JOURNAL.PONE.0028394

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22164283 AND SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

22164283

1 reference