BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase (Q24298631)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

title

BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

0 references

0 references

BRCA1 associated RING domain 1

1 reference

positive regulation of apoptotic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Charles Edward Jefford

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

Philip Berardi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

Jian-Yu Wu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

Laetitia Cartier

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

Karl-Heinz Krause

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

Irmgard Irminger-Finger

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

1 May 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

3726-3736

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782130 AND SRC:MED&resulttype=core&format=json

The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity

9 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

BARD1 expression during spermatogenesis is associated with apoptosis and hormonally regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Mutation of phosphoserine 389 affects p53 function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

BRCA1-dependent and independent functions of BARD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

In vitro repression of Brca1-associated RING domain gene, Bard1, induces phenotypic changes in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Mutational analysis of BARD1 in familial breast cancer patients in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

DNA-dependent protein kinase and checkpoint kinase 2 synergistically activate a latent population of p53 upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Nuclear-cytoplasmic translocation of BARD1 is linked to its apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Mutation screening of the BARD1 gene: evidence for involvement of the Cys557Ser allele in hereditary susceptibility to breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Molecular interaction map of the mammalian cell cycle control and DNA repair systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Regulation of p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

The CDK7-cycH-p36 Complex of Transcription Factor IIH Phosphorylates p53, Enhancing Its Sequence-Specific DNA Binding Activity In Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Tumorigenesis in mice carrying a truncating Brca1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

p53 Phosphorylation: biochemical and functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Prediction of central nervous system embryonal tumour outcome based on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Development and characterization of a clinically useful animal model of epithelial ovarian cancer in the Fischer 344 rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Dissection of signal-regulated transcriptional modules by signaling pathway interference in oncogene-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Genetic steps of mammalian homologous repair with distinct mutagenic consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

The BRCT Domain Is a Phospho-Protein Binding Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

Ionizing radiation exposure results in up-regulation of Ku70 via a p53/ataxia-telangiectasia-mutated protein-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

7 January 2021

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

7 January 2021

A third-generation lentivirus vector with a conditional packaging system

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

7 January 2021

Factors in the causation and incidence of ovarian cancer

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

7 January 2021

Germline mutations of the BRCA1-associated ring domain (BARD1) gene in breast and breast/ovarian families negative for BRCA1 and BRCA2 alterations

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

7 January 2021

Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated abl kinase is an ATM-dependent process

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208491

7 January 2021