Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC (Q24296725)

Leucine rich repeat containing 8 VRAC subunit E

1 reference

Leucine rich repeat containing 8 VRAC subunit B

1 reference

Leucine rich repeat containing 8 VRAC subunit C

1 reference

Leucine rich repeat containing 8 VRAC subunit D

1 reference

anion transmembrane transport

1 reference

Florian Ullrich

2

Florian

Ullrich

1 reference

30 October 2023

Nancy Mah

6

Nancy

Mah

1 reference

30 October 2023

Tobias Stauber

9

Tobias

Stauber

1 reference

30 October 2023

Thomas J Jentsch

10

Thomas J

Jentsch

1 reference

30 October 2023

1

Felizia K Voss

Felizia K

Voss

1 reference

30 October 2023

Jonas Münch

3

Jonas

Münch

1 reference

30 October 2023

Katina Lazarow

4

Katina

Lazarow

1 reference

30 October 2023

Darius Lutter

5

Darius

Lutter

1 reference

30 October 2023

Miguel A Andrade-Navarro

7

Miguel A

Andrade-Navarro

1 reference

30 October 2023

Jens P von Kries

8

Jens P

von Kries

1 reference

A congenital mutation of the novel gene LRRC8 causes agammaglobulinemia in humans

30 October 2023

language of work or name

English

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publication date

9 May 2014

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published in

Science

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volume

344

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issue

6184

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page(s)

634-8

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cites work

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Multiplex genome engineering using CRISPR/Cas systems

20 April 2017

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Structure of the connexin 26 gap junction channel at 3.5 A resolution

20 April 2017

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Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

20 April 2017

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RNA-guided human genome engineering via Cas9

20 April 2017

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LRRC8 proteins share a common ancestor with pannexins, and may form hexameric channels involved in cell-cell communication

20 April 2017

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https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Cell swelling activates separate taurine and chloride channels in Ehrlich mouse ascites tumor cells

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https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Swelling-induced catecholamine secretion recorded from single chromaffin cells

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https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Volume-activated Cl- currents in different mammalian non-excitable cell types.

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Characterization of regulatory volume behavior by fluorescence quenching in human corneal epithelial cells

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death.

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Differential activation of the volume-sensitive cation channel TRP12 (OTRPC4) and volume-regulated anion currents in HEK-293 cells

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https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Control of volume-sensitive chloride channel inactivation by the coupled action of intracellular chloride and extracellular protons

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https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Case 2: differential diagnosis of acute gout and bacterial infection

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https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

The biochemistry and function of pannexin channels

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

LRRC8 extracellular domain is composed of 17 leucine-rich repeats.

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Green fluorescent protein-based halide indicators with improved chloride and iodide affinities

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Properties of volume-regulated anion channels in mammalian cells.

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Regions involved in the opening of CIC-2 chloride channel by voltage and cell volume

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Swelling-activated organic osmolyte efflux: a new role for anion channels

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Rescue of volume-regulated anion current by bestrophin mutants with altered charge selectivity

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Tissue-specific subnetworks and characteristics of publicly available human protein interaction databases.

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

A swelling‐activated chloride current in rat sympathetic neurones

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Volume sensitivity of the bestrophin family of chloride channels

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Hypotonic activation of volume-sensitive outwardly rectifying chloride channels in cultured PASMCs is modulated by SGK.

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Physiology of cell volume regulation in vertebrates.

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Swelling-induced taurine transport: relationship with chloride channels, anion-exchangers and other swelling-activated transport pathways

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

QuantPrime--a flexible tool for reliable high-throughput primer design for quantitative PCR.

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https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Factor for adipocyte differentiation 158 gene disruption prevents the body weight gain and insulin resistance induced by a high-fat diet.

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Anion-sensitive fluorophore identifies the Drosophila swell-activated chloride channel in a genome-wide RNA interference screen

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021

Carbenoxolone inhibits volume-regulated anion conductance in cultured rat cortical astroglia

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1252826

7 January 2021