14-3-3 amplifies and prolongs adrenergic stimulation of HERG K channel activity (Q24294353)

5 July 2017

title

14-3-3 amplifies and prolongs adrenergic stimulation of HERG K channel activity (English)

1 reference

negative regulation of peptidyl-serine dephosphorylation

5 July 2017

main subject

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902309

positive regulation of peptidyl-serine dephosphorylation

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902310

regulation of peptidyl-serine dephosphorylation

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902308

Potassium voltage-gated channel subfamily H member 2

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Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

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Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta

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regulation of potassium ion transmembrane transport

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author name string

Anna Kagan

1

1 reference

5 July 2017

Yonathan F Melman

2

1 reference

5 July 2017

Andrew Krumerman

3

1 reference

5 July 2017

Thomas V McDonald

4

1 reference

5 July 2017

language of work or name

English

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publication date

1 April 2002

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5 July 2017

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5 July 2017

volume

21

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5 July 2017

issue

8

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5 July 2017

page(s)

1889-1898

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Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

5 July 2017

cites work

1 reference

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Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers

19 March 2017

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Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation

19 March 2017

1 reference

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AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex

19 March 2017

1 reference

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Modulation of A-type potassium channels by a family of calcium sensors

19 March 2017

1 reference

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MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

19 March 2017

1 reference

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

19 March 2017

1 reference

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Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

19 March 2017

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14-3-3 Binding to Na /H exchanger isoform-1 is associated with serum-dependent activation of Na /H exchange

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

A structural basis for drug-induced long QT syndrome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

14-3-3 ζ Negatively Regulates Raf-1 Activity by Interactions with the Raf-1 Cysteine-rich Domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

A minK-HERG complex regulates the cardiac potassium current I(Kr)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

The complexity of Raf-1 regulation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

A beta2 adrenergic receptor signaling complex assembled with the Ca2 channel Cav1.2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

The AKT3 potassium channel protein interacts with the AtPP2CA protein phosphatase 2C

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

KChAP as a chaperone for specific K( ) channels

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

19 March 2017

1 reference

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14-3-3 proteins: structure, function, and regulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

14-3-3 proteins; bringing new definitions to scaffolding

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

27 September 2017

I(Kr): the hERG channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Regulation of the cardiac repolarizing HERG potassium channel by protein kinase A.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

The long QT syndromes: genetic basis and clinical implications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Modulation of ion channels: a "current" view of AKAPs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

The zeta isoform of 14-3-3 proteins interacts with the third intracellular loop of different alpha2-adrenergic receptor subtypes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

27 September 2017

1 reference

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The long QT syndrome: ion channel diseases of the heart

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

The molecular genetics of the long QT syndrome: genes causing fainting and sudden death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Phosphorylation of presynaptic and postsynaptic calcium channels by cAMP-dependent protein kinase in hippocampal neurons

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

The 14-3-3 protein binds its target proteins with a common site located towards the C-terminus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Structure and sites of phosphorylation of 14-3-3 protein: role in coordinating signal transduction pathways.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Modulation of the Ca(2 )-activated Cl(-) channel by 14-3-3epsilon

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

14-3-3 proteins double the number of outward-rectifying K channels available for activation in tomato cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

A dynamically regulated 14-3-3, Slob, and Slowpoke potassium channel complex in Drosophila presynaptic nerve terminals

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125975

Glucocorticoid receptor interaction with 14-3-3 and Raf-1, a proposed mechanism for cross-talk of two signal transduction pathways

29 November 2018

1 reference

12 December 2020

The dominant negative LQT2 mutation A561V reduces wild-type HERG expression

1 reference

12 December 2020

Analysis of the cyclic nucleotide binding domain of the HERG potassium channel and interactions with KCNE2

1 reference

12 December 2020

Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II

1 reference

12 December 2020

Identification of soluble protein phosphatases that dephosphorylate voltage-sensitive sodium channels in rat brain

1 reference

12 December 2020

Protein phosphorylation and cardiac function: cholinergic-adrenergic interaction

1 reference

12 December 2020

Cyclic AMP regulates the HERG K( ) channel by dual pathways

1 reference

12 December 2020

A plethora of mechanisms in the HERG-related long QT syndrome. Genetics meets electrophysiology

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/21.8.1889

1 reference

5 July 2017

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5 July 2017

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