Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation (Q24293752)

Polycystin 2, transient receptor potential cation channel

1 reference

Phosphofurin acidic cluster sorting protein 1

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protein localization to plasma membrane

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author

Bernhard Schermer

8

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Thomas Benzing

2

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Albrecht Kramer-Zucker

9

object named as

Albrecht Kramer-Zucker

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author name string

Michael Köttgen

1

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Thomas Simmen

3

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Robert Tauber

4

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Björn Buchholz

5

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Sylvain Feliciangeli

6

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Tobias B Huber

7

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Katja Höpker

10

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Katia Carmine Simmen

11

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Christoph Carl Tschucke

12

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Richard Sandford

13

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Emily Kim

14

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Gary Thomas

15

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Gerd Walz

Furin at the cutting edge: from protein traffic to embryogenesis and disease

16

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language of work or name

English

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publication date

23 February 2005

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published in

The EMBO Journal

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volume

24

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issue

4

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page(s)

705-16

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cites work

1 reference

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Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein

19 March 2017

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Polycystin-2 is an intracellular calcium release channel

19 March 2017

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Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2

19 March 2017

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PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic.

19 March 2017

1 reference

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Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2 -permeable nonselective cation channel

19 March 2017

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Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene

19 March 2017

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Interaction between RGS7 and polycystin

19 March 2017

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Regulation of stability and function of the epithelial Na channel (ENaC) by ubiquitination

19 March 2017

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Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

19 March 2017

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Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

19 March 2017

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Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism

19 March 2017

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

19 March 2017

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Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals

19 March 2017

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14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity

19 March 2017

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PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization

19 March 2017

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Native polycystin 2 functions as a plasma membrane Ca2 -permeable cation channel in renal epithelia

19 March 2017

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Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease

19 March 2017

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Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex

19 March 2017

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TRP channels as cellular sensors

19 March 2017

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The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

7 April 2017

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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

7 April 2017

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PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis

7 April 2017

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ER-to-Golgi transport and cytoskeletal interactions in animal cells

27 September 2017

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TRPV4 calcium entry channel: a paradigm for gating diversity.

27 September 2017

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Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing

27 September 2017

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27 September 2017

The Birth of a Channel

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27 September 2017

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The role of regulated CFTR trafficking in epithelial secretion

27 September 2017

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Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity

27 September 2017

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Interferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription

27 September 2017

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The central role of the trans-Golgi network as a gateway of the early secretory pathway: physiologic vs nonphysiologic protein transit

27 September 2017

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Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

27 September 2017

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Tubulogenesis in the developing mammalian kidney

27 September 2017

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ER transport signals and trafficking of potassium channels and receptors

27 September 2017

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Molecular structure and physiological function of chloride channels

27 September 2017

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Distinct subcellular expression of endogenous polycystin-2 in the plasma membrane and Golgi apparatus of MDCK cells

27 September 2017

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Physiology, phylogeny, and functions of the TRP superfamily of cation channels

27 September 2017

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Trans-Golgi network sorting

27 September 2017

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Role of ER export signals in controlling surface potassium channel numbers

27 September 2017

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Identification and characterization of polycystin-2, the PKD2 gene product

27 September 2017

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Regulation of endosome sorting by a specific PP2A isoform

27 September 2017

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Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail

27 September 2017

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Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

27 September 2017

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Inhibition of CK2 activity by TGF-beta1 promotes IkappaB-alpha protein stabilization and apoptosis of immortalized hepatocytes

27 September 2017

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Casein kinase type II is involved in the inhibition by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription

30 May 2018

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30 May 2018

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Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.

30 May 2018

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Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X.

21 January 2018

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Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells

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21 January 2018

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