ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics (Q24293687)

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24 December 2019

title

ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics (English)

1 reference

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Alsin Rho guanine nucleotide exchange factor ALS2

24 December 2019

main subject

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ALS2 C-terminal like

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endosome organization

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ALS2 C-terminal like

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author

Asako Otomo

3

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24 December 2019

author name string

Kyoko Suzuki-Utsunomiya

1

1 reference

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24 December 2019

Shinji Hadano

2

1 reference

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24 December 2019

Ryota Kunita

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17239822 AND SRC:MED&resulttype=core&format=json

24 December 2019

Hikaru Mizumura

5

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24 December 2019

Hitoshi Osuga

6

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24 December 2019

Joh-E Ikeda

7

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24 December 2019

language of work or name

English

0 references

publication date

11 January 2007

1 reference

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Biochemical and Biophysical Research Communications

24 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17239822 AND SRC:MED&resulttype=core&format=json

24 December 2019

volume

354

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24 December 2019

issue

2

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24 December 2019

page(s)

491-497

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ALS2CL, the novel protein highly homologous to the carboxy-terminal half of ALS2, binds to Rab5 and modulates endosome dynamics

24 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

Vps9 domain-containing proteins: activators of Rab5 GTPases from yeast to neurons

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

Rab5 regulates motility of early endosomes on microtubules

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

Rab proteins as membrane organizers

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

Molecular biology of amyotrophic lateral sclerosis: insights from genetics

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome trafficking

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2006.12.229

7 January 2021

10.1016/J.BBRC.2006.12.229

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17239822 AND SRC:MED&resulttype=core&format=json

24 December 2019

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