Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses (Q24293580)

intrinsic apoptotic signaling pathway in response to DNA damage

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Sirtuin 1

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Hypermethylated in cancer 1

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6

Stephen B Baylin

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author name string

Wen Yong Chen

1

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David H Wang

2

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Raywhay Chiu Yen

3

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Jianyuan Luo

4

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Wei Gu

A genetic model for colorectal tumorigenesis

5

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language of work or name

English

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publication date

4 November 2005

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published in

Cell

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volume

123

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issue

3

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page(s)

437-48

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cites work

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PUMA induces the rapid apoptosis of colorectal cancer cells

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Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

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p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

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The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif

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Sirtuins: Sir2-related NAD-dependent protein deacetylases

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