Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2 (Q24293326)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12552091 AND SRC:MED&resulttype=core&format=json

17 December 2019

title

Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2 (English)

1 reference

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17 December 2019

0 references

1 reference

Signal transducer and activator of transcription 5B

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estrogen receptor 1

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signal transducer and activator of transcription 3

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Suppressor of cytokine signaling 2

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somatotropin

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Interleukin 6

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growth hormone receptor signaling pathway via JAK-STAT

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1 reference

4

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17 December 2019

Tsu-Hui Low

6

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17 December 2019

author name string

K C Leung

1

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17 December 2019

N Doyle

2

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17 December 2019

M Ballesteros

3

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17 December 2019

C K W Watts

5

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17 December 2019

G M Leong

7

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17 December 2019

R J M Ross

8

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17 December 2019

K K Y Ho

9

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17 December 2019

language of work or name

English

0 references

publication date

27 January 2003

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Proceedings of the National Academy of Sciences of the United States of America

17 December 2019

published in

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17 December 2019

volume

100

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17 December 2019

issue

3

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17 December 2019

page(s)

1016-1021

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Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor

17 December 2019

cites work

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

19 March 2017

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The nuclear receptor superfamily: the second decade

6 April 2017

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Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)

19 March 2017

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Identification of suppressors of cytokine signaling (SOCS) proteins in human gestational tissues: differential regulation is associated with the onset of labor

19 March 2017

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Suppressor of cytokine signaling (SOCS)-3 protein interacts with the insulin-like growth factor-I receptor

19 March 2017

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Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B

19 March 2017

1 reference

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Gigantism in mice lacking suppressor of cytokine signalling-2

19 March 2017

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SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms

19 March 2017

1 reference

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Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern

19 March 2017

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A short isoform of the human growth hormone receptor functions as a dominant negative inhibitor of the full-length receptor and generates large amounts of binding protein

19 March 2017

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Functional interactions between Stat5 and the glucocorticoid receptor

19 March 2017

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Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

19 March 2017

1 reference

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Molecular mechanisms of action of steroid/thyroid receptor superfamily members

19 March 2017

1 reference

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Jaks and STATs: biological implications

7 April 2017

1 reference

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Structural design and molecular evolution of a cytokine receptor superfamily

7 April 2017

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The suppressors of cytokine signalling (SOCS).

7 April 2017

1 reference

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Cross-talk between signal transducer and activator of transcription 3 and estrogen receptor signaling

27 September 2017

1 reference

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Distribution and abundance of messenger ribonucleic acid for growth hormone receptor isoforms in human tissues

27 September 2017

1 reference

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The role of STAT proteins in growth hormone signaling

27 September 2017

1 reference

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Stimulation of endogenous GH and interleukin-6 receptors selectively activates different Jaks and Stats, with a Stat5 specific synergistic effect of dexamethasone.

27 September 2017

1 reference

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Regulators of growth hormone signaling

27 September 2017

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The route of estrogen replacement therapy confers divergent effects on substrate oxidation and body composition in postmenopausal women

27 September 2017

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Specific DNA binding of Stat5, but not of glucocorticoid receptor, is required for their functional cooperation in the regulation of gene transcription

27 September 2017

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Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription

27 September 2017

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Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice

27 September 2017

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Effect of growth hormone on carbohydrate and lipid metabolism

27 September 2017

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The pharmacokinetics, safety and endocrine effects of authentic biosynthetic human growth hormone in normal subjects

27 September 2017

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Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-hour growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women

27 September 2017

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Prolactin receptors in human breast cancer cells in long-term tissue culture

27 September 2017

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Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

27 September 2017

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Oral estrogen antagonizes the metabolic actions of growth hormone in growth hormone-deficient women

30 May 2018

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Estrogens exert route- and dose-dependent effects on insulin-like growth factor (IGF)-binding protein-3 and the acid-labile subunit of the IGF ternary complex

29 November 2018

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Regulation of growth hormone receptor gene expression

29 November 2018

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Growth hormone (GH)-deficient men are more responsive to GH replacement therapy than women

29 November 2018

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Cross-talk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms

29 November 2018

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12 December 2020

Inhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadate

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12 December 2020

Differential activation of Stat3 and Stat5 by distinct regions of the growth hormone receptor

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12 December 2020

Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate

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12 December 2020

Mapping of a cytoplasmic domain of the human growth hormone receptor that regulates rates of inactivation of Jak2 and Stat proteins

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12 December 2020

Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation

1 reference

12 December 2020

Studies with a growth hormone antagonist and dual-fluorescent confocal microscopy demonstrate that the full-length human growth hormone receptor, but not the truncated isoform, is very rapidly internalized independent of Jak2-Stat5 signaling

1 reference

12 December 2020

A comparison of transcriptional activation by ER alpha and ER beta

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12 December 2020

Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family

1 reference

12 December 2020

Growth hormone regulation of SOCS-2, SOCS-3, and CIS messenger ribonucleic acid expression in the rat

1 reference

12 December 2020

A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase

1 reference

https://api.crossref.org/works/10.1073/PNAS.0337600100

7 January 2021

Identification of Suppressors of Cytokine Signaling (SOCS) Proteins in Human Gestational Tissues: Differential Regulation Is Associated with the Onset of Labor

1 reference

https://api.crossref.org/works/10.1073/PNAS.0337600100

7 January 2021

Mutation of the SHP-2 Binding Site in Growth Hormone (GH) Receptor Prolongs GH-Promoted Tyrosyl Phosphorylation of GH Receptor, JAK2, and STAT5B

1 reference

https://api.crossref.org/works/10.1073/PNAS.0337600100

7 January 2021

Growth Enhancement in Suppressor of Cytokine Signaling 2 (SOCS-2)-Deficient Mice Is Dependent on Signal Transducer and Activator of Transcription 5b (STAT5b)

1 reference

https://api.crossref.org/works/10.1073/PNAS.0337600100

7 January 2021

Identifiers

DOI

10.1073/PNAS.0337600100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12552091 AND SRC:MED&resulttype=core&format=json

17 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12552091 AND SRC:MED&resulttype=core&format=json

17 December 2019

PubMed publication ID

12552091

1 reference