Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha (Q24290442)

GOA release 2020-03-11

triglyceride homeostasis

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RAR-related orphan receptor alpha

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Jean-Charles Fruchart

5

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Helene Duez

object named as

H Duez

2

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Jean Mariani

object named as

J Mariani

7

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Bart Staels

object named as

B Staels

9

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author name string

E Raspé

1

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P Gervois

3

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C Fiévet

4

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S Besnard

6

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A Tedgui

Journal of Biological Chemistry

8

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language of work or name

English

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publication date

26 January 2001

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published in

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volume

276

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issue

4

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page(s)

2865-71

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cites work

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Hypertriglyceridaemia associated with an abnormal triglyceride-rich lipoprotein carrying excess apolipoprotein C-III-2

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Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo

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Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E

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Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III

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Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase

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Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia

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Activation of CAAT enhancer-binding protein delta (C/EBPdelta) by interleukin-1 negatively influences apolipoprotein C-III expression.

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Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates

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Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells

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DNA binding and transcription activation specificity of hepatocyte nuclear factor 4

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Transactivation of the ApoCIII promoter by ATF-2 and repression by members of the Jun family

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Apo CIII gene transcription is regulated by a cytokine inducible NF-kappa B element

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Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

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Determinants of target gene specificity for ROR alpha 1: monomeric DNA binding by an orphan nuclear receptor

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The ExDression Pattern of the Orphan Nuclear Receptor RORβ in the Developing and Adult Rat Nervous System Suggests a Role in the Processing of Sensory Information and in Circadian Rhythm

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Functional Interactions between Retinoic Acid Receptor-related Orphan Nuclear Receptor (RORα) and the Retinoic Acid Receptors in the Regulation of the γF-Crystallin Promoter

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Orphan nuclear receptor ROR alpha-deficient mice display the cerebellar defects of staggerer

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Transcriptional regulation of apolipoprotein A-I gene expression by the nuclear receptor RORalpha

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Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor

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Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene

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Transcriptional Activation and Repression by ROR , an Orphan Nuclear Receptor Required for Cerebellar Development

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7 January 2021

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Repression of apoC‐III gene expression by TNFα involves C/EBPδ/NF‐IL6β via an IL‐1 independent pathway

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Complex Interactions between SP1 Bound to Multiple Distal Regulatory Sites and HNF-4 Bound to the Proximal Promoter Lead to Transcriptional Activation of Liver-Specific Human APOCIII Gene

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7 January 2021

Binding specificity and modulation of the human ApoCIII promoter activity by heterodimers of ligand-dependent nuclear receptors

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7 January 2021

Identification of natural monomeric response elements of the nuclear receptor RZR/ROR. They also bind COUP-TF homodimers

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Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice

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7 January 2021

Triglyceride: the forgotten risk factor

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7 January 2021

Severe atherosclerosis and hypoalphalipoproteinemia in the staggerer mouse, a mutant of the nuclear receptor RORalpha

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7 January 2021

Triglyceride-rich lipoprotein remnant particles and risk of atherosclerosis

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7 January 2021