The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes (Q24290189)

GOA release 2020-03-11

response to nutrient

1 reference

GOA release 2020-03-11

author

Eric Lander

16

0 references

Tiinamaija Tuomi

11

T Tuomi

0 references

Leif Groop

15

L Groop

0 references

Mark Joseph Daly

14

M Daly

0 references

David Altshuler

1

D Altshuler

0 references

Mia M. Gaudet

12

D Gaudet

0 references

Thomas J. Hudson

13

T J Hudson

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author name string

J N Hirschhorn

2

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M Klannemark

3

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C M Lindgren

4

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M C Vohl

5

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J Nemesh

6

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C R Lane

7

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S F Schaffner

8

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S Bolk

9

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C Brewer

10

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language of work or name

English

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publication date

September 2000

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number of pages

5

1 reference

Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes

inferred from page(s)

published in

Nature Genetics

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volume

26

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issue

1

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page(s)

76-80

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cites work

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An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance

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A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus

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Frequency of Mutations of Insulin Receptor Gene in Japanese Patients With NIDDM

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Missense mutation of amylin gene (S20G) in Japanese NIDDM patients

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Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians

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A missense mutation of the muscle glycogen synthase gene (M416V) is associated with insulin resistance in the Japanese population

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A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

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Missense mutations in the pancreatic islet beta cell inwardly rectifying K channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

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Association of polymorphisms in the beta2-adrenergic receptor gene with obesity, hypertriglyceridaemia, and diabetes mellitus

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7 January 2021

Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles

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Tumour necrosis factor-alpha gene promoter polymorphism and decreased insulin resistance

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The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes

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7 January 2021

The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes

1 reference

7 January 2021

Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.

1 reference

7 January 2021

Impact of the Peroxisome Proliferator Activated Receptor γ2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus

1 reference

7 January 2021

Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus

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A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test

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Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

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Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

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Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-gamma 2 on thiazolidinedione-induced adipogenesis

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7 January 2021

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

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Obesity associated with a mutation in a genetic regulator of adipocyte differentiation

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Metabolic consequences of a family history of NIDDM (the Botnia study): evidence for sex-specific parental effects

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Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

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Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies

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Impaired fasting glucose or impaired glucose tolerance. What best predicts future diabetes in Mauritius?

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Fluorescence energy transfer detection as a homogeneous DNA diagnostic method

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Genetic association mapping based on discordant sib pairs: the discordant-alleles test

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