Cancer pharmacogenomics: strategies and challenges (Q24289309)

Europe PubMed Central

title

Cancer pharmacogenomics: strategies and challenges (English)

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1 reference

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Nancy J Cox

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Mark J Ratain

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object named as

Mark J Ratain

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author name string

Heather E Wheeler

1

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Michael L Maitland

2

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M Eileen Dolan

Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing

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language of work or name

English

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publication date

January 2013

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published in

Nature Reviews Genetics

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volume

14

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issue

1

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page(s)

23-34

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cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

27 September 2017

Bayesian clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Genome-wide discovery of loci influencing chemotherapy cytotoxicity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Heritability and linkage analysis of sensitivity to cisplatin-induced cytotoxicity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Extreme discordant phenotype methodology: an intuitive approach to clinical pharmacogenetics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Two-stage extreme phenotype sequencing design for discovering and testing common and rare genetic variants: efficiency and power

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Polymorphisms of the SLCO1B1 gene predict methotrexate-related toxicity in childhood acute lymphoblastic leukemia.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668552

Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response

30 May 2018

1 reference

Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial.

21 January 2018

1 reference

Validation and reduction of FACT/GOG-Ntx subscale for platinum/paclitaxel-induced neurologic symptoms: a gynecologic oncology group study.

21 January 2018

1 reference

Design of phase II cancer trials using a continuous endpoint of change in tumor size: application to a study of sorafenib and erlotinib in non small-cell lung cancer

21 January 2018

1 reference

A time to keep and a time to cast away categories of tumor response.

21 January 2018

1 reference

Model-based prediction of phase III overall survival in colorectal cancer on the basis of phase II tumor dynamics.

21 January 2018

1 reference

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

21 January 2018

1 reference

Genetic polymorphisms of CYP2D6 10 and CYP2C19 2, 3 are not associated with prognosis, endometrial thickness, or bone mineral density in Japanese breast cancer patients treated with adjuvant tamoxifen

21 January 2018

1 reference

Bayesian meta-analysis and meta-regression for gene-disease associations and deviations from Hardy-Weinberg equilibrium.

21 January 2018

1 reference

Upward bias in odds ratio estimates from genome-wide association studies

21 January 2018

1 reference

Computational neuroanatomy of speech production.

21 January 2018

1 reference

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

21 January 2018

1 reference

MC1R germline variants confer risk for BRAF-mutant melanoma

21 January 2018

1 reference

UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG3352

1 reference

Dimensions Publication ID

1052968546

0 references

1 reference

1 reference

PubMed publication ID

23183705

1 reference