New insights into the role of nuclear factor-KB, a ubiquitous transcription factor in the initiation of diseases (Q23923136)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

8 December 2019

15 October 2024

1 reference

title

New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

NIOSH Health Effects Laboratory Division

8 December 2019

New insights into the role of nuclear factor-KB, a ubiquitous transcription factor in the initiation of diseases (English)

1 reference

15 October 2024

object named as

HELD

1 reference

25 September 2023

1 reference

29 March 2020

1 reference

29 March 2020

2

V Castranova

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

8 December 2019

3

X Shi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

8 December 2019

author name string

F Chen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

8 December 2019

L M Demers

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

8 December 2019

language of work or name

English

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publication date

1 January 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

full work available at URL

8 December 2019

http://www.clinchem.org/cgi/content/abstract/45/1/7

1 reference

29 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

8 December 2019

volume

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

8 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

7-17

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9895331 AND SRC:MED&resulttype=core&format=json

on focus list of Wikimedia project

8 December 2019

Wikimedia–NIOSH collaboration

0 references

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Essential role of NF-kappa B activation in silica-induced inflammatory mediator production in macrophages

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Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells.

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Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes

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Redox signalling by transcription factors NF-kappa B and AP-1 in lymphocytes.

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

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Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis

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Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokine synthesis

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Ceramide-induced nuclear translocation of NF-kappa B is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts

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A thiol antioxidant regulates IgE isotype switching by inhibiting activation of nuclear factor-κB

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The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

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Identification and characterization of an IkappaB kinase

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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7 January 2021

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

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The NF-kappa B inhibitor, tepoxalin, suppresses surface expression of the cell adhesion molecules CD62E, CD11b/CD18 and CD106

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7 January 2021

Enhanced TNF alpha production by monocytic-like cells exposed to dengue virus antigens

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7 January 2021

t(14;19)/BCL3 rearrangements in lymphoproliferative disorders: a review of 23 cases

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Dexamethasone attenuates NF-kappa B DNA binding activity without inducing I kappa B levels in rat brain in vivo

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Malignant tumors and AIDS

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The current state of the prevention of HBV infection, the carrier state and hepatocellular carcinoma

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Activate NF-kappa B or die?

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Role of Rel/NF-kappaB transcription factors during the outgrowth of the vertebrate limb.

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Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis.

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Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B

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Expression of relB is required for the development of thymic medulla and dendritic cells

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7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

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Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

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In vivo transfection of cis element “decoy” against nuclear factor- κB binding site prevents myocardial infarction

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Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

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Germline configuration of nfkb2, c-rel and bcl3 in childhood acute lymphoblastic leukemia (ALL)

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A threshold nuclear level of the v-Rel oncoprotein is required for transformation of avian lymphocytes.

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The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor

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Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

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NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176

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Cell type-specific transactivation of the VCAM-1 promoter through an NF-kappa B enhancer motif

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Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B.

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Nitric oxide attenuates vascular smooth muscle cell activation by interferon-gamma. The role of constitutive NF-kappa B activity

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Characterization of IkappaB kinases. IkappaB-alpha is not phosphorylated by Raf-1 or protein kinase C isozymes, but is a casein kinase II substrate

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7 January 2021

Manipulation of distinct NFkappaB proteins alters interleukin-1beta-induced human rheumatoid synovial fibroblast prostaglandin E2 formation

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7 January 2021

Interleukin-4 suppression of tumor necrosis factor alpha-stimulated E-selectin gene transcription is mediated by STAT6 antagonism of NF-kappaB

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7 January 2021

Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB.

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7 January 2021

Flanking sequences for the human intercellular adhesion molecule-1 NF-kappaB response element are necessary for tumor necrosis factor alpha-induced gene expression

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7 January 2021

Selective Up-regulation of Cytokine-induced RANTES Gene Expression in Lung Epithelial Cells by Overexpression of IκBR

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The 90-kDa Ribosomal S6 Kinase (pp90rsk) Phosphorylates the N-terminal Regulatory Domain of IκBα and Stimulates Its Degradation in Vitro

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Inhibition of Endothelial Vascular Cell Adhesion Molecule-1 Expression by Nitric Oxide Involves the Induction and Nuclear Translocation of IκBα

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7 January 2021

IkappaBalpha overexpression delays tumor formation in v-rel transgenic mice.

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7 January 2021

Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

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7 January 2021

Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses

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7 January 2021

Cellular mechanisms of action of therapeutic nitric oxide donors

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7 January 2021

Inhibition of NF-kappaB DNA binding by nitric oxide

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Requirement for NF-κB in osteoclast and B-cell development

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A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

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7 January 2021

Cell death mechanisms and the immune system

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7 January 2021

Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-kappa B

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7 January 2021

Regulation of gene expression with double-stranded phosphorothioate oligonucleotides

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7 January 2021

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

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7 January 2021

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

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7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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7 January 2021

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

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7 January 2021

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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7 January 2021

Requirement of NF-κB Activation to Suppress p53-Independent Apoptosis Induced by Oncogenic Ras

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7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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7 January 2021

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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7 January 2021

Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C

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7 January 2021

Dengue virus replication in human hepatoma cells activates NF-kappaB which in turn induces apoptotic cell death

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7 January 2021

Inhibition of human immunodeficiency virus type 1 replication in vitro by a novel combination of anti-Tat single-chain intrabodies and NF-kappa B antagonists

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7 January 2021

Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors

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ch-IAP1, a Member of the Inhibitor-of-Apoptosis Protein Family, Is a Mediator of the Antiapoptotic Activity of the v-Rel Oncoprotein

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7 January 2021

The signal response of IkappaB alpha is regulated by transferable N- and C-terminal domains

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7 January 2021

Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

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7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

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7 January 2021

The Role of Nuclear Factor- κ B in Cytokine Gene Regulation

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7 January 2021

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines

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7 January 2021

Clinically relevant findings

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7 January 2021

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

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7 January 2021

Deletion Variants within the NF-kB Activation Domain of the LMP1 Oncogene in Acquired Immunodeficiency Syndrome-Related Large Cell Lymphomas, in Prelymphomas and Atypical Lymphoproliferations

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7 January 2021

OpenCitations bibliographic resource ID

Identifiers

DOI

10.1093/CLINCHEM/45.1.7

1 reference

5 October 2020

0 references

2313767

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2313767

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2313767