Sorbitol dehydrogenase (Q22680170)

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mammalian protein found in Homo sapiens

polyol dehydrogenase
ribitol dehydrogenase
sorbitol dehydrogenase
epididymis secretory sperm binding protein Li 95n
(R,R)-butanediol dehydrogenase
L-iditol 2-dehydrogenase
xylitol dehydrogenase
SORD

Language	Label	Description	Also known as
English	Sorbitol dehydrogenase	mammalian protein found in Homo sapiens	polyol dehydrogenase ribitol dehydrogenase sorbitol dehydrogenase epididymis secretory sperm binding protein Li 95n (R,R)-butanediol dehydrogenase L-iditol 2-dehydrogenase xylitol dehydrogenase SORD

Statements

1 reference

13 November 2019

UniProt protein ID

NAD(P)-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q00796

GroES-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q00796

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Polyketide synthase, enoylreductase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Alcohol dehydrogenase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Alcohol dehydrogenase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Alcohol dehydrogenase, zinc-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

1 reference

9 May 2019

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

zinc ion binding

determination method or standard

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

metal ion binding

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

L-iditol 2-dehydrogenase activity

determination method or standard

8 references

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

1 January 2018

Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

1 January 2018

Purification and characterization of human liver sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

1 January 2018

Polyol-pathway enzymes of human brain. Partial purification and properties of sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

1 January 2018

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

1 January 2018

Polyol-pathway enzymes of human brain. Partial purification and properties of sorbitol dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

D-xylulose reductase activity

determination method or standard

carbohydrate binding

determination method or standard

1 reference

9 May 2019

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

identical protein binding

determination method or standard

3 references

9 May 2019

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

L-iditol 2-dehydrogenase activity

determination method or standard

6 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Purification and characterization of human liver sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Polyol-pathway enzymes of human brain. Partial purification and properties of sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

(R,R)-butanediol dehydrogenase activity

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

D-xylulose reductase activity

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

ribitol 2-dehydrogenase activity

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

cell projection

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

mitochondrial membranes

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

determination method or standard

extracellular exosome

determination method or standard

4 references

17 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

17 October 2017

Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00796&geneProductId=UniProtKB:Q00796

determination method or standard

extracellular space

determination method or standard

1 reference

9 May 2019

Sorbitol dehydrogenase (EC.1.1.1.14) polymorphism in human seminal plasma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

extracellular exosome

determination method or standard

3 references

9 May 2019

Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

biological process

flagellated sperm motility

determination method or standard

3 references

9 May 2019

Polyol pathway in human epididymis and semen

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

response to cadmium ion

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

response to copper ion

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

sorbitol catabolic process

determination method or standard

4 references

9 May 2019

Purification and characterization of human liver sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Polyol-pathway enzymes of human brain. Partial purification and properties of sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

fructose biosynthetic process

determination method or standard

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Purification and characterization of human liver sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

9 May 2019

Polyol-pathway enzymes of human brain. Partial purification and properties of sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

glucuronate catabolic process to xylulose 5-phosphate

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

response to osmotic stress

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

L-xylitol metabolic process

determination method or standard

1 reference

9 May 2019

Purification and characterization of human liver sorbitol dehydrogenase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

response to nutrient levels

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

glucose metabolic process

determination method or standard

1 reference

9 May 2019

Sorbitol dehydrogenase: structure, function and ligand design

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

L-xylitol catabolic process

determination method or standard

1 reference

9 May 2019

Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

response to hormone

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

sorbitol metabolic process

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00796

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000267814

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000267814

ENSP00000453904

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453904

ENSP00000452731

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452731

ENSP00000453122

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453122

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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