interferon alpha 2 (Q22677926)

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mammalian protein found in Homo sapiens

interferon alpha 2b
interferon alpha A
alpha-2a interferon
leIF A
interferon alpha-2
interferon alpha 2a
Interferon alpha-A
IFN-alpha-2
IFNA2(24-188)
Interferon-α2

Language	Label	Description	Also known as
English	interferon alpha 2	mammalian protein found in Homo sapiens	interferon alpha 2b interferon alpha A alpha-2a interferon leIF A interferon alpha-2 interferon alpha 2a Interferon alpha-A IFN-alpha-2 IFNA2(24-188) Interferon-α2

Statements

1 reference

13 November 2019

UniProt protein ID

protein fragment

0 references

interferon alpha/beta/delta

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01563

four-helical cytokine-like, core

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01563

prepro-interferon alpha-2

0 references

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

type I interferon receptor binding

determination method or standard

1 reference

24 April 2018

At least three human type alpha interferons: structure of alpha 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01563&geneProductId=UniProtKB:P01563

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

cytokine receptor binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

extracellular region

determination method or standard

biological process

apoptotic process

determination method or standard

1 reference

8 April 2019

Recombinant IFN-alpha (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

defense response

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

negative regulation of viral entry into host cell

determination method or standard

1 reference

8 April 2019

The Sin3a repressor complex is a master regulator of STAT transcriptional activity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

response to exogenous dsRNA

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

cell-cell signaling

determination method or standard

1 reference

8 April 2019

Recombinant IFN-alpha (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

negative regulation of T-helper 2 cell cytokine production

determination method or standard

1 reference

8 April 2019

Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

blood coagulation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

positive regulation of peptidyl-serine phosphorylation of STAT protein

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

negative regulation of gene expression

determination method or standard

1 reference

8 April 2019

Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

positive regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

HCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

natural killer cell activation involved in immune response

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

cell surface receptor signaling pathway

determination method or standard

1 reference

8 April 2019

At least three human type alpha interferons: structure of alpha 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

B cell proliferation

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

humoral immune response

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

type I interferon signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

B cell differentiation

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

positive regulation of phosphorylation

determination method or standard

1 reference

8 April 2019

HCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

inflammatory response

determination method or standard

1 reference

8 April 2019

Recombinant IFN-alpha (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

negative regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

negative regulation of T cell differentiation

determination method or standard

1 reference

8 April 2019

Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

T cell activation involved in immune response

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

innate immune response

determination method or standard

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01563&geneProductId=UniProtKB:P01563

determination method or standard

cytokine-mediated signaling pathway

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

positive regulation of tyrosine phosphorylation of STAT protein

determination method or standard

1 reference

8 April 2019

The Sin3a repressor complex is a master regulator of STAT transcriptional activity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

regulation of signaling receptor activity

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

adaptive immune response

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01563

determination method or standard

https://www.uniprot.org/uniprot/P01563#PRO_0000016360

0 references

said to be the same as

interferon Alfa-2a, recombinant

0 references

Identifiers

MeSH descriptor ID

subject named as

Interferon alpha-2

0 references

D12.644.276.374.440.890.250.500

0 references

D12.776.467.374.440.890.250.500

0 references

D23.529.374.440.890.250.500

0 references

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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