Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin (Q22254045)

GOA release 2020-03-11

JNK cascade

1 reference

GOA release 2020-03-11

Y F Liu

1

Y F

Liu

1 reference

PubMed

8 February 2023

D Dorow

series ordinal

2

author given names

D

author last names

Dorow

1 reference

PubMed

8 February 2023

J Marshall

series ordinal

3

author given names

J

author last names

Marshall

1 reference

PubMed

Journal of Biological Chemistry

8 February 2023

language of work or name

English

0 references

publication date

23 June 2000

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published in

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volume

275

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issue

25

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page(s)

19035-40

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cites work

Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.C000180200

Huntington's disease. Pathogenesis and management

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Selective sparing of a class of striatal neurons in Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.C000180200

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.C000180200

Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.C000180200

From Src Homology domains to other signaling modules: proposal of the 'protein recognition code'.

21 January 2018

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SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

Huntingtin interacts with a family of WW domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2

21 January 2018

1 reference

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The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

21 January 2018

1 reference

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MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

Differential Activation of Two JNK Activators, MKK7 and SEK1, by MKN28-derived Nonreceptor Serine/Threonine Kinase/Mixed Lineage Kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

Transcription factor ATF2 regulation by the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

21 January 2018

1 reference

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

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Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

Expression of mixed lineage kinase 2 in germ cells of the testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons.

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Role of the Jun Kinase Pathway in the Regulation of c-Jun Expression and Apoptosis in Sympathetic Neurons

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

inferred from DOI database lookup

7 January 2021

based on heuristic

Cellular localization of huntingtin in striatal and cortical neurons in rats: lack of correlation with neuronal vulnerability in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1074/JBC.C000180200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.C000180200

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Fatcat ID

release_xne5eonk55hlheur3r2eitm3te

0 references