Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein (Q22253357)

GOA release 2020-03-11

Cell division cycle 42

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GOA release 2020-03-11

GBD domain binding

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GOA release 2020-03-11

A S Kim

1

Annette S.

Kim

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7 February 2023

L T Kakalis

2

Lazaros T.

Kakalis

1 reference

7 February 2023

N Abdul-Manan

3

Norzehan

Abdul-Manan

1 reference

7 February 2023

G A Liu

4

Grace A.

Liu

1 reference

7 February 2023

M K Rosen

5

Michael K.

Rosen

1 reference

The GTPase superfamily: a conserved switch for diverse cell functions

7 February 2023

language of work or name

English

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publication date

9 March 2000

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published in

Nature

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volume

404

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issue

6774

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page(s)

151-8

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cites work

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7 January 2021

Rho GTPases and the actin cytoskeleton

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7 January 2021

Signaling to actin dynamics

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7 January 2021

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

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7 January 2021

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

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7 January 2021

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

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7 January 2021

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

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7 January 2021

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

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7 January 2021

The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation

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7 January 2021

Trifluoroethanol and colleagues: cosolvents come of age. Recent studies with peptides and proteins.

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7 January 2021

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

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7 January 2021

Helix propagation and N-cap propensities of the amino acids measured in alanine-based peptides in 40 volume percent trifluoroethanol

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7 January 2021

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7 January 2021

Activation of the yeast Arp2/3 complex by Bee1p, a WASP-family protein

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7 January 2021

The Wiskott-Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex

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7 January 2021

Actin polymerization: Where the WASP stings

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7 January 2021

Cooperative Interaction between the Three Strands of a Designed Antiparallel β-Sheet

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7 January 2021

Tyrosine phosphorylation of the Wiskott-Aldrich syndrome protein by Lyn and Btk is regulated by CDC42

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7 January 2021

Scanning of the Wiskott-Aldrich syndrome (WAS) gene: identification of 18 novel alterations including a possible mutation hotspot at Arg86 resulting in thrombocytopenia, a mild WAS phenotype

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7 January 2021

X-linked thrombocytopenia and Wiskott-Aldrich syndrome are allelic diseases with mutations in the WASP gene

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7 January 2021

WASP gene mutations in Wiskott-Aldrich syndrome and X-linked thrombocytopenia

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7 January 2021

Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus

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7 January 2021

Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo

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7 January 2021

Increasing complexity of Ras signaling.

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7 January 2021

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

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7 January 2021

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

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7 January 2021

Activation of Raf as a result of recruitment to the plasma membrane

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7 January 2021

Coupling of local folding to site-specific binding of proteins to DNA

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7 January 2021

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

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7 January 2021

A Suite of Triple Resonance NMR Experiments for the Backbone Assignment of 15N, 13C, 2H Labeled Proteins with High Sensitivity

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7 January 2021

A general method for assigning NMR spectra of denatured proteins using 3D HC(CO)NH-TOCSY triple resonance experiments.

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7 January 2021

Measurement of HN-H alpha J couplings in calcium-free calmodulin using new 2D and 3D water-flip-back methods

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7 January 2021

Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional 13C labeling

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7 January 2021

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

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7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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7 January 2021

Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin

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7 January 2021

AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

1 reference

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

7 January 2021