Defects in mucosal immunity leading to Crohn's disease (Q22242645)

Europe PubMed Central

title

Defects in mucosal immunity leading to Crohn's disease (English)

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Gena M. Cobrin

1

Gena M

Cobrin

1 reference

PubMed

PubMed publication ID

16048555

8 February 2023

Maria T. Abreu

series ordinal

2

author given names

Maria T

author last names

Abreu

1 reference

PubMed

PubMed publication ID

16048555

Functional variants of OCTN cation transporter genes are associated with Crohn disease

8 February 2023

language of work or name

English

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publication date

August 2005

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published in

Immunological Reviews

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volume

206

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issue

1

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page(s)

277-295

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cites work

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Natural regulatory T cells and self-tolerance

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

CD4 T regulatory cells from the colonic lamina propria of normal mice inhibit proliferation of enterobacteria-reactive, disease-inducing Th1-cells from scid mice with colitis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Interleukin 18 is a potent proliferative factor for intestinal mucosal lymphocytes in Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Comparative study of ASCA (Anti-Saccharomyces cerevisiae antibody) assays in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

ANCA pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Transmembrane TNF-alpha, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Mucosal flora in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Distinct inflammatory mechanisms mediate early versus late colitis in mice

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Expansion of CD8 T cells with regulatory function after interaction with intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Failure to induce oral tolerance to a soluble protein in patients with inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Crohn's disease is associated with a toll-like receptor-9 polymorphism

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

A risk haplotype in the Solute Carrier Family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Trichuris suis therapy for active ulcerative colitis: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Anti-interleukin-12 antibody for active Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Association of TNF-α-857C with Inflammatory Bowel Disease in the Australian Population

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Immunologic regulation of toll-like receptors in gut epithelium.

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Update in inflammatory bowel disease pathogenesis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Innate immunity of the gut: mucosal defense in health and disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

THE EXTRA-INTESTINAL COMPLICATIONS OF CROHNʼS DISEASE AND ULCERATIVE COLITIS: A STUDY OF 700 PATIENTS

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Intestinal permeability and postheparin plasma diamine oxidase activity in the prediction of Crohn's disease relapse

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

The expression of IL-12 p40 and its homologue, Epstein-Barr virus-induced gene 3, in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Inflammatory bowel disease-associated gene expression in intestinal epithelial cells by differential cDNA screening and mRNA display

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease.

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

A long-term cohort study of nonsteroidal anti-inflammatory drug use and disease activity in outpatients with inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

beta-Defensin-3 and -4 in intestinal epithelial cells display increased mRNA expression in ulcerative colitis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

TNF-alpha -308A promoter polymorphism is associated with enhanced TNF-alpha production and inflammatory activity in Crohn's patients with fistulizing disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

A polymorphism in the TNF-alpha promoter gene is associated with pediatric onset and colonic location of Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Toll pathway-dependent blockade of CD4 CD25 T cell-mediated suppression by dendritic cells

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Host-bacterial mutualism in the human intestine

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Immunity, inflammation, and allergy in the gut.

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Glycan foraging in vivo by an intestine-adapted bacterial symbiont

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like receptor 4-MD-2 complex

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria.

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Smoking and Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

The granuloma in Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Histopathological evaluation of colonic mucosal biopsy specimens in chronic inflammatory bowel disease: diagnostic implications

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Intestinal permeability

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Thickness of adherent mucus gel on colonic mucosa in humans and its relevance to colitis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Cytokine gene polymorphisms in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

CARD4/NOD1 is not involved in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Chronic inflammatory bowel disease in children: a complex problem in management

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Analysis of mucosal gene expression in inflammatory bowel disease by parallel oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Investigation of the prognostic value of TNF-alpha gene polymorphism among patients treated with infliximab, and the effects of infliximab therapy on TNF-alpha production and apoptosis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Activation of a unique population of CD8( ) T cells by intestinal epithelial cells.

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Failure to induce oral tolerance in Crohn's and ulcerative colitis patients: possible genetic risk

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

CD4 CD25bright T cells in human intestinal lamina propria as regulatory cells

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Defects in CD8 regulatory T cells in the lamina propria of patients with inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021

Nonsteroidal anti-inflammatory drugs activate quiescent inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00293.X

7 January 2021