Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals (Q22122053)

Europe PubMed Central

title

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals (English)

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2

Adrian Bird

Adrian

Bird

1 reference

Dimensions Publication ID

Dimensions

6 February 2023

1

Rudolf Jaenisch

Rudolf

Jaenisch

1 reference

Dimensions Publication ID

Dimensions

1015302967

De novo methylation and expression of retroviral genomes during mouse embryogenesis.

6 February 2023

language of work or name

English

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publication date

March 2003

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published in

Nature Genetics

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volume

33

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issue

3s

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page(s)

245-254

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cites work

1 reference

7 January 2021

X inactivation, differentiation, and DNA methylation

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7 January 2021

Chemistry. How are alkynes scrambled?

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7 January 2021

Epigenetics: regulation through repression

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7 January 2021

Above and within the genome: epigenetics past and present

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7 January 2021

The role of DNA methylation in mammalian epigenetics

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7 January 2021

Imprinting and the epigenetic asymmetry between parental genomes

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7 January 2021

Genomic imprinting: parental influence on the genome

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7 January 2021

DNA methylation patterns and epigenetic memory

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7 January 2021

Chromatin modification and epigenetic reprogramming in mammalian development

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7 January 2021

DNA methylation and imprinting: why bother?

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7 January 2021

Demethylation of the zygotic paternal genome

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7 January 2021

Active demethylation of the paternal genome in the mouse zygote

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7 January 2021

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells

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7 January 2021

De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines

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7 January 2021

Comparison of DNA methylation patterns among mouse cell lines by restriction landmark genomic scanning

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7 January 2021

The DNA methyltransferases of mammals

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7 January 2021

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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7 January 2021

Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene

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7 January 2021

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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7 January 2021

Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila.

1 reference

7 January 2021

Dnmt3L and the establishment of maternal genomic imprints

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7 January 2021

Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells

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7 January 2021

DNA methylation in Drosophila melanogaster.

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7 January 2021

DNA of Drosophila melanogaster contains 5-methylcytosine

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7 January 2021

DNA hypomethylation can activate Xist expression and silence X-linked genes.

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7 January 2021

Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos

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7 January 2021

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

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7 January 2021

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

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7 January 2021

Transcription of IAP endogenous retroviruses is constrained by cytosine methylation

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7 January 2021

DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals.

1 reference

7 January 2021

Cytosine methylation and mammalian development

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7 January 2021

CpG-rich islands and the function of DNA methylation

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7 January 2021

CpG islands in vertebrate genomes

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7 January 2021

CpG islands as gene markers in the human genome.

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7 January 2021

An alternative promoter in the mouse major histocompatibility complex class II I-Abeta gene: implications for the origin of CpG islands

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7 January 2021

Bidirectional gene organization: a common architectural feature of the human genome.

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7 January 2021

Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1.

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7 January 2021

Identification and characterization of the DNA binding domain of CpG-binding protein

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7 January 2021

Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation

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7 January 2021

Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation

1 reference

7 January 2021

Sp1 elements protect a CpG island from de novo methylation

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7 January 2021

Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island

1 reference

7 January 2021

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

7 January 2021

The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription

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7 January 2021

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

1 reference

7 January 2021

Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

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7 January 2021

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

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7 January 2021

Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase

1 reference

7 January 2021

Review: chromatin structural features and targets that regulate transcription

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7 January 2021

Heterochromatin: new possibilities for the inheritance of structure

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7 January 2021

Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

1 reference

7 January 2021

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

1 reference

7 January 2021

CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

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7 January 2021

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

1 reference

7 January 2021

Effects of DNA methylation on DNA-binding proteins and gene expression.

1 reference

7 January 2021

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

1 reference

7 January 2021

Identification and characterization of a family of mammalian methyl-CpG binding proteins

1 reference

7 January 2021

The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

1 reference

7 January 2021

Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

1 reference

7 January 2021

MeCP2 and MBD2 expression during normal and pathological growth of the human mammary gland

1 reference

7 January 2021

In vivo repression of an erythroid-specific gene by distinct corepressor complexes

1 reference

7 January 2021

Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation

1 reference

7 January 2021

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

1 reference

7 January 2021

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1 reference

7 January 2021

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1 reference

7 January 2021

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

1 reference

7 January 2021

1 reference

7 January 2021

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

1 reference

7 January 2021

Gene silencing quantitatively controls the function of a developmental trans-activator

1 reference

7 January 2021

Molecular mechanisms of gene silencing mediated by DNA methylation

1 reference

7 January 2021

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

1 reference

7 January 2021

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

1 reference

7 January 2021

Functional consequences of Rett syndrome mutations on human MeCP2.

1 reference

7 January 2021

DNA recognition by the methyl-CpG binding domain of MeCP2.

1 reference

7 January 2021

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

1 reference

7 January 2021

Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3

1 reference

7 January 2021

Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain

1 reference

7 January 2021

Role for DNA methylation in the control of cell type specific maspin expression

1 reference

7 January 2021

DNA methylation at promoter regions regulates the timing of gene activation in Xenopus laevis embryos

1 reference

7 January 2021

X-chromosome inactivation: counting, choice and initiation

1 reference

7 January 2021

Igf2 imprinting does not require its own DNA methylation or H19 RNA.

1 reference

7 January 2021

X-chromosome inactivation and the search for chromosome-wide silencers

1 reference

7 January 2021

The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1

1 reference

7 January 2021

CTCF, a candidate trans-acting factor for X-inactivation choice

1 reference

7 January 2021

Mechanisms of genomic imprinting

1 reference

7 January 2021

Role for DNA methylation in genomic imprinting

1 reference

7 January 2021

Loss of methylation activates Xist in somatic but not in embryonic cells

1 reference

7 January 2021

The ubiquitin ligase Hyperplastic discs negatively regulates hedgehog and decapentaplegic expression by independent mechanisms

1 reference

7 January 2021

Epigenetic reprogramming in mouse primordial germ cells

1 reference

7 January 2021

Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.

1 reference

7 January 2021

X-Inactivation and histone H4 acetylation in embryonic stem cells

1 reference

7 January 2021

A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation

1 reference

7 January 2021

Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation

1 reference

7 January 2021

Nuclear cloning and epigenetic reprogramming of the genome

1 reference

7 January 2021

Large offspring syndrome in cattle and sheep

1 reference

7 January 2021

Early death of mice cloned from somatic cells

1 reference

7 January 2021

Cloned mice have an obese phenotype not transmitted to their offspring

1 reference

7 January 2021

Nuclear transplantation: lessons from frogs and mice

1 reference

7 January 2021

Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos

1 reference

7 January 2021

Aberrant methylation of donor genome in cloned bovine embryos

1 reference

7 January 2021

Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos

1 reference

7 January 2021

Oct4 distribution and level in mouse clones: consequences for pluripotency

1 reference

7 January 2021

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

1 reference

7 January 2021

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

1 reference

7 January 2021

Epigenetic instability in ES cells and cloned mice

1 reference

7 January 2021

Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei

1 reference

7 January 2021

Faithful expression of imprinted genes in cloned mice.

1 reference

7 January 2021

X-Chromosome inactivation in cloned mouse embryos

1 reference

7 January 2021

Cloning of mice to six generations

1 reference

7 January 2021

Extension of cell life-span and telomere length in animals cloned from senescent somatic cells

1 reference

7 January 2021

Generation of mice from wild-type and targeted ES cells by nuclear cloning

1 reference

7 January 2021

Mouse cloning with nucleus donor cells of different age and type

1 reference

7 January 2021

Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation

1 reference

7 January 2021

Monoclonal mice generated by nuclear transfer from mature B and T donor cells

1 reference

7 January 2021

Genetic stability and modulation of metazoan nuclei transplanted into eggs and oocytes

1 reference

7 January 2021

Genetic reprogramming following nuclear transplantation in Amphibia

1 reference

7 January 2021

Developmental biology. Don't clone humans!

1 reference

7 January 2021

Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy

1 reference

7 January 2021

The fundamental role of epigenetic events in cancer

1 reference

7 January 2021

Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

1 reference

7 January 2021

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

1 reference

7 January 2021

The 5-methylcytosine content of DNA from human tumors

1 reference

7 January 2021

DNA methylation and cancer

1 reference

7 January 2021

Mutagenic and epigenetic effects of DNA methylation

1 reference

7 January 2021

Cancer epigenetics comes of age

1 reference

7 January 2021

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

1 reference

7 January 2021

High frequencies of ICF syndrome-like pericentromeric heterochromatin decondensation and breakage in chromosome 1 in a chorionic villus sample

1 reference

7 January 2021

DNA hypomethylation leads to elevated mutation rates

1 reference

7 January 2021

Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells.

1 reference

7 January 2021

Gene silencing in mammalian cells and the spread of DNA methylation

1 reference

7 January 2021

Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

1 reference

7 January 2021

The control of flowering by vernalization

1 reference

7 January 2021

The molecular basis of vernalization: the central role of FLOWERING LOCUS C (FLC)

1 reference

7 January 2021

The FLF MADS box gene: a repressor of flowering in Arabidopsis regulated by vernalization and methylation

1 reference

7 January 2021

The VERNALIZATION 2 gene mediates the epigenetic regulation of vernalization in Arabidopsis.

1 reference

7 January 2021

The Polycomb group--no longer an exclusive club?

1 reference

7 January 2021

DNA methylation decreases in aging but not in immortal cells

1 reference

7 January 2021

Decreased methylation of the major mouse long interspersed repeated DNA during aging and in myeloma cells

1 reference

7 January 2021

Creation of genomic methylation patterns

1 reference

7 January 2021

Epigenetic regulation of an IAP retrotransposon in the aging mouse: progressive demethylation and de-silencing of the element by its repetitive induction

1 reference

7 January 2021

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

1 reference

7 January 2021

CpG island methylator phenotype in colorectal cancer

1 reference

7 January 2021

CpG island methylator phenotypes in aging and cancer.

1 reference

7 January 2021

Genetic effects of methylation diets

1 reference

7 January 2021

Folate, Methionine, and Alcohol Intake and Risk of Colorectal Adenoma

1 reference

7 January 2021

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

1 reference

7 January 2021

The role of micronutrients in DNA synthesis and maintenance

1 reference

7 January 2021

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group

1 reference

7 January 2021

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.

1 reference

7 January 2021

Alterations in expression and methylation of specific genes in livers of rats fed a cancer promoting methyl-deficient diet

1 reference

7 January 2021

1 reference

7 January 2021

Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.

1 reference

7 January 2021

Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage

1 reference

7 January 2021

Hypervariable yellow (Ahvy), a new murine agouti mutation: Ahvy displays the largest variation in coat color phenotypes of all known agouti alleles

1 reference

7 January 2021

Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring

1 reference

7 January 2021

Epigenetic inheritance at the agouti locus in the mouse

1 reference

7 January 2021

Human morbid genetics revisited: relevance of epigenetics

1 reference

7 January 2021

An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability

1 reference

7 January 2021

Tumour class prediction and discovery by microarray-based DNA methylation analysis

1 reference

7 January 2021

Translating the Histone Code

1 reference

7 January 2021

Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

1 reference

7 January 2021

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

1 reference

7 January 2021

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

1 reference

7 January 2021

Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues

1 reference

7 January 2021

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

1 reference

7 January 2021

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

1 reference

7 January 2021

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

1 reference

7 January 2021

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

1 reference

7 January 2021

Suppression of intestinal neoplasia by DNA hypomethylation.

1 reference

7 January 2021

The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

1 reference

7 January 2021

DNA modification mechanisms and gene activity during development

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG1089

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1015302967

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Fatcat ID

release_itu5dcynsrfopgxbgehp5ug3qa

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Fatcat

https://api.fatcat.wiki/v0/release/itu5dcynsrfopgxbgehp5ug3qa

24 November 2022

mapped directly with Wikidata item

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12610534

1 reference

Consolidated OpenCitations Corpus – April 2017