Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC (Q22010522)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

title

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

BUB1 mitotic checkpoint serine/threonine kinase B

12 December 2019

main subject

kinetochore

0 references

1 reference

mitotic cell cycle checkpoint signaling

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1

G K Chan

G K

Chan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

5

T J Yen

T J

Yen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

S A Jablonski

2

S A

Jablonski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

V Sudakin

series ordinal

3

author given names

V

author last names

Sudakin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

J C Hittle

series ordinal

4

author given names

J C

author last names

Hittle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

language of work or name

English

0 references

publication date

1 September 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

published in

Journal of Cell Biology

1 reference

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12 December 2019

volume

146

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

page(s)

941-954

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores

12 December 2019

cites work

1 reference

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Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

19 March 2017

1 reference

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Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E

19 March 2017

1 reference

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The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

19 March 2017

1 reference

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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

19 March 2017

1 reference

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Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events

19 March 2017

1 reference

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Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1

19 March 2017

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Mutations of mitotic checkpoint genes in human cancers

19 March 2017

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MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

19 March 2017

1 reference

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Identification of a human mitotic checkpoint gene: hsMAD2

19 March 2017

1 reference

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The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase

19 March 2017

1 reference

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The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

19 March 2017

1 reference

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CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

19 March 2017

1 reference

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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

19 March 2017

1 reference

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Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast

19 March 2017

1 reference

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19 March 2017

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Budding yeast Cdc20: a target of the spindle checkpoint.

19 March 2017

1 reference

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CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

19 March 2017

1 reference

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The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

19 March 2017

1 reference

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CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

Feedback control of mitosis in budding yeast

19 March 2017

1 reference

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Identification of a cullin homology region in a subunit of the anaphase-promoting complex

19 March 2017

1 reference

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How proteolysis drives the cell cycle

19 March 2017

1 reference

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Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores

19 March 2017

1 reference

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Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members

19 March 2017

1 reference

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The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae

19 March 2017

1 reference

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Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

19 March 2017

1 reference

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Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage

7 April 2017

1 reference

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How cells get the right chromosomes

7 April 2017

1 reference

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Mitotic forces control a cell-cycle checkpoint

7 April 2017

1 reference

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The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis

7 April 2017

1 reference

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Activation of the MKK/ERK pathway during somatic cell mitosis: direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen.

12 September 2017

1 reference

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Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity

12 September 2017

1 reference

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The vertebrate cell kinetochore and its roles during mitosis

12 September 2017

1 reference

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Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase

12 September 2017

1 reference

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Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

CENP-E function at kinetochores is essential for chromosome alignment.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

Force generation by microtubule assembly/disassembly in mitosis and related movements

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

Kinetochore function: molecular motors, switches and gates

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

A thousand and one protein kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169490

Localization of the Drosophila checkpoint control protein Bub3 to the kinetochore requires Bub1 but not Zw10 or Rod.

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1083/JCB.146.5.941

p34cdc2 kinase is localized to distinct domains within the mitotic apparatus

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10477750

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.146.5.941

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json

12 December 2019

PubMed publication ID

10477750

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10477750 AND SRC:MED&resulttype=core&format=json