Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein (Q22009957)

6 February 2023

B Aghazadeh

2

Behzad

Aghazadeh

1 reference

6 February 2023

G A Liu

3

Grace A.

Liu

1 reference

6 February 2023

A Majumdar

4

Ananya

Majumdar

1 reference

6 February 2023

O Ouerfelli

5

Ouathek

Ouerfelli

1 reference

6 February 2023

K A Siminovitch

6

Katherine A.

Siminovitch

1 reference

6 February 2023

M K Rosen

7

Michael K.

Rosen

1 reference

Rho GTPases and the actin cytoskeleton

6 February 2023

language of work or name

English

0 references

publication date

27 May 1999

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published in

Nature

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volume

399

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issue

6734

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page(s)

379-83

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cites work

1 reference

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

21 January 2018

1 reference

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

21 January 2018

1 reference

The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation

21 January 2018

1 reference

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

Structural basis for the interaction of Ras with RalGDS

21 January 2018

1 reference

Definition of the switch surface in the solution structure of Cdc42Hs

21 January 2018

1 reference

Use of a fluorescence spectroscopic readout to characterize the interactions of Cdc42Hs with its target/effector, mPAK-3.

21 January 2018

1 reference

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

21 January 2018

1 reference

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

1 reference

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

21 January 2018

1 reference

Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization

21 January 2018

1 reference

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

21 January 2018

1 reference

Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

21 January 2018

1 reference

Ras/Rap effector specificity determined by charge reversal

21 January 2018

1 reference

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

21 January 2018

1 reference

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

21 January 2018

1 reference

Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases

21 January 2018

1 reference

A novel regulator of p21-activated kinases

21 January 2018

1 reference

An (H)C(CO)NH-TOCSY pulse scheme for sequential assignment of protonated methyl groups in otherwise deuterated (15)N, (13)C-labeled proteins

21 January 2018

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin

21 January 2018

1 reference

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

21 January 2018

1 reference

AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

21 January 2018

1 reference

Production and Incorporation of15N,13C,2H (1H-δ1 Methyl) Isoleucine into Proteins for Multidimensional NMR Studies

21 January 2018

1 reference

A Suite of Triple Resonance NMR Experiments for the Backbone Assignment of 15N, 13C, 2H Labeled Proteins with High Sensitivity

21 January 2018

1 reference

Rac GTPase interacts with GAPs and target proteins through multiple effector sites.

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identification of the binding surface on Cdc42Hs for p21-activated kinase

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

1 reference