The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase (Q22009088)

protein autophosphorylation

GOA release 2020-03-11

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GOA release 2020-03-11

C J Howlett

1

C J

Howlett

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7 February 2023

S A Bisson

2

S A

Bisson

1 reference

7 February 2023

M E Resek

3

M E

Resek

1 reference

7 February 2023

A W Tigley

4

A W

Tigley

1 reference

7 February 2023

S M Robbins

5

S M

Robbins

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Biochemical and Biophysical Research Communications

7 February 2023

language of work or name

English

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publication date

2 April 1999

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published in

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volume

257

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issue

1

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page(s)

129-38

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cites work

Hormone-conditional transformation by fusion proteins of c-Abl and its transforming variants

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https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Redox-linked ligand-independent cell surface triggering for extensive protein tyrosine phosphorylation

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https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Specific association of phosphatidylinositol 3-kinase with the protooncogene product Cbl in Fc gamma receptor signaling

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Examination of B lymphoid cell lines for membrane immunoglobulin-stimulated tyrosine phosphorylation and src-family tyrosine kinase mRNA expression

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https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

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https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Cbl: complex formation and functional implications

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https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

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https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Yeast two-hybrid in vivo association of the Src kinase Lyn with the proto-oncogene product Cbl but not with the p85 subunit of PI 3-kinase

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

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Rapid T-cell receptor-mediated tyrosine phosphorylation of p120, an Fyn/Lck Src homology 3 domain-binding protein

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptors

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https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways

1 reference

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7 January 2021

T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38.

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin

1 reference

https://api.crossref.org/works/10.1006/BBRC.1999.0427

7 January 2021

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Identifiers

DOI

10.1006/BBRC.1999.0427

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Fatcat ID

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