Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein (Q22004024)

GTPase activator activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

S M Soisson

1

S M

Soisson

1 reference

7 February 2023

A S Nimnual

2

A S

Nimnual

1 reference

7 February 2023

M Uy

3

M

Uy

1 reference

7 February 2023

D Bar-Sagi

4

D

Bar-Sagi

1 reference

7 February 2023

J Kuriyan

5

J

Kuriyan

1 reference

Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1.

7 February 2023

language of work or name

English

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publication date

16 October 1998

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published in

Cell

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volume

95

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issue

2

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page(s)

259-68

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cites work

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The Sos (Son of sevenless) protein

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Proteins regulating Ras and its relatives

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The structural basis of the activation of Ras by Sos

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The GTPase superfamily: conserved structure and molecular mechanism

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The Dbl family of oncogenes

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The role of the PH domain in the signal-dependent membrane targeting of Sos.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Structure of the Sec7 domain of the Arf exchange factor ARNO

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Regulation of Sos Activity by Intramolecular Interactions

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Isolation of a new human oncogene from a diffuse B-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Activation of the exchange factor Ras-GRF by calcium requires an intact Dbl homology domain

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Rho GTPases and the Actin Cytoskeleton

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Role of Substrates and Products of PI 3-kinase in Regulating Activation of Rac-Related Guanosine Triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Protein structure comparison by alignment of distance matrices

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1)

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

High affinity binding of the pleckstrin homology domain of mSos1 to phosphatidylinositol (4,5)-bisphosphate

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Structure of the Guanine Nucleotide Exchange Factor Sec7 Domain of Human Arno and Analysis of the Interaction with ARF GTPase

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Coupling of Ras and Rac Guanosine Triphosphatases Through the Ras Exchanger Sos

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

N Terminus of Sos1 Ras Exchange Factor: Critical Roles for the Dbl and Pleckstrin Homology Domains

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Improved Fourier coefficients for maps using phases from partial structures with errors

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The 1.7 Å crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Crystal structure of the EF-Tu˙EF-Ts complex from Thermus thermophilus

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

Direct involvement of the small GTP-binding protein Rho in lbc oncogene function

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

[31] Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)81756-0

7 January 2021

10.1016/S0092-8674(00)81756-0

Identifiers

DOI

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Fatcat ID

release_uhx7tqxkpfgl7pwebpuimwxe5u

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