Ubiquitin protein ligase E3A (Q21992532)

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mammalian protein found in Mus musculus

HECT-type ubiquitin transferase E3A
ubiquitin-protein ligase E3A
Ube3a
E6-AP ubiquitin protein ligase
ubiquitin conjugating enzyme E3A
oncogenic protein-associated protein E6-AP

Language	Label	Description	Also known as
English	Ubiquitin protein ligase E3A	mammalian protein found in Mus musculus	HECT-type ubiquitin transferase E3A ubiquitin-protein ligase E3A Ube3a E6-AP ubiquitin protein ligase ubiquitin conjugating enzyme E3A oncogenic protein-associated protein E6-AP

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

HECT, E3 ligase catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08759

Ubiquitin-protein ligase E3A

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08759

HECT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

ubiquitin protein ligase activity

determination method or standard

4 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

transcription coactivator activity

determination method or standard

1 reference

8 April 2019

Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

metal ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

ubiquitin-protein transferase activity

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

transferase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

determination method or standard

1 reference

8 April 2019

Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

proteasome complex

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

biological process

androgen receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

rhythmic process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

protein K48-linked ubiquitination

determination method or standard

regulation of circadian rhythm

determination method or standard

3 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

determination method or standard

1 reference

8 April 2019

Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

ovarian follicle development

determination method or standard

1 reference

8 April 2019

Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

positive regulation of phosphatidylinositol 3-kinase signaling

determination method or standard

1 reference

8 April 2019

Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

prostate gland growth

determination method or standard

2 references

regulation of ubiquitin-dependent protein catabolic process

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

response to cocaine

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

response to hydrogen peroxide

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

cellular response to brain-derived neurotrophic factor stimulus

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

response to progesterone

determination method or standard

progesterone receptor signaling pathway

determination method or standard

protein polyubiquitination

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

ubiquitin-dependent protein catabolic process

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

positive regulation of protein ubiquitination

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

protein autoubiquitination

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08759

determination method or standard

Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08759

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08759

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

20 February 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000103161

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000103161

ENSMUSP00000143859

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143859

ENSMUSP00000143962

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143962

ENSMUSP00000143896

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143896

ENSMUSP00000144148

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144148

ENSMUSP00000144220

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144220

ENSMUSP00000144398

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144398

ENSMUSP00000144453

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144453

ENSMUSP00000144645

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144645

ENSMUSP00000146524

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000146524

ENSMUSP00000146673

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000146673

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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