SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (Q21991666)

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mammalian protein found in Mus musculus

integrase interactor 1 protein
BRG1-associated factor 47
Smarcb1
BAF47
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
mSNF5
SNF5 homolog

Language	Label	Description	Also known as
English	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	mammalian protein found in Mus musculus	integrase interactor 1 protein BRG1-associated factor 47 Smarcb1 BAF47 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 mSNF5 SNF5 homolog

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Chromatin-remodeling complex component Sfh1/SNF5

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z0H3

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method or standard

protein binding

determination method or standard

4 references

14 February 2019

Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

SRG3 interacts directly with the major components of the SWI/SNF chromatin remodeling complex and protects them from proteasomal degradation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

RNA polymerase I core promoter sequence-specific DNA binding

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

transcription coactivator activity

determination method or standard

1 reference

10 September 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

Tat protein binding

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

protein binding

determination method or standard

5 references

10 September 2018

Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

10 September 2018

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

10 September 2018

SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

10 September 2018

SRG3 interacts directly with the major components of the SWI/SNF chromatin remodeling complex and protects them from proteasomal degradation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

1 reference

10 September 2018

An essential switch in subunit composition of a chromatin remodeling complex during neural development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

nuclear chromosome

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

1 reference

10 September 2018

An essential switch in subunit composition of a chromatin remodeling complex during neural development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

3 references

27 February 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

27 February 2018

Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

SWI/SNF complex

determination method or standard

2 references

27 February 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

27 February 2018

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

SWI/SNF complex

determination method or standard

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

determination method or standard

biological process

cell differentiation

determination method or standard

1 reference

14 February 2019

The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

regulation of transcription by RNA polymerase II

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

nervous system development

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

determination method or standard

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

negative regulation of cell population proliferation

determination method or standard

3 references

14 February 2019

Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

14 February 2019

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

single stranded viral RNA replication via double stranded DNA intermediate

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

positive regulation by host of viral transcription

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

positive regulation of DNA-binding transcription factor activity

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

positive regulation of histone H4 acetylation

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

negative regulation of histone H3-K9 dimethylation

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

negative regulation of histone H3-K9 trimethylation

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

positive regulation of glucose mediated signaling pathway

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

positive regulation of histone H3-K9 acetylation

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

RNA polymerase I preinitiation complex assembly

determination method or standard

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

chromatin organization

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0H3

determination method or standard

negative regulation of cell population proliferation

determination method or standard

4 references

10 September 2018

Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

10 September 2018

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

10 September 2018

Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0H3&geneProductId=UniProtKB:Q9Z0H3

determination method or standard

cell differentiation

determination method or standard

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000000925

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000000925

ENSMUSP00000112463

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000112463

ENSMUSP00000115388

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000115388

ENSMUSP00000123093

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000123093

Sitelinks

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Multilingual sites(0 entries)

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