Intraflagellar transport 88 (Q21985507)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61371

Tetratricopeptide repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tetratricopeptide repeat family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

3 references

9 May 2019

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

kinesin binding

1 reference

31 January 2018

Different roles for KIF17 and kinesin II in photoreceptor development and maintenance

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

1 reference

31 January 2018

intraciliary transport particle B

5 references

9 May 2019

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Characterization of mouse IFT complex B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

ciliary basal body

The BBSome controls IFT assembly and turnaround in cilia

5 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Ofd1, a human disease gene, regulates the length and distal structure of centrioles

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

1 reference

9 May 2019

kinocilium

1 reference

9 May 2019

Ciliary proteins link basal body polarization to planar cell polarity regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

outer acrosomal membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

acrosomal membrane

1 reference

9 May 2019

GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

ciliary base

3 references

31 January 2018

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

trans-Golgi network

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

ciliary tip

4 references

9 May 2019

The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

axonemal basal plate

1 reference

9 May 2019

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

axoneme

5 references

9 May 2019

Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Ciliary proteins link basal body polarization to planar cell polarity regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Intraflagellar transport molecules in ciliary and nonciliary cells of the retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

1 reference

9 May 2019

cilium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

13 references

9 May 2019

TAS

9 May 2019

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

9 May 2019

Ofd1, a human disease gene, regulates the length and distal structure of centrioles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Characterization of mouse IFT complex B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

motile cilium

1 reference

11 October 2018

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

non-motile cilium

1 reference

31 January 2018

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

centriole

5 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

31 January 2018

Ofd1, a human disease gene, regulates the length and distal structure of centrioles

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

centrosome

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Characterization of mouse IFT complex B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

centriole

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

9 May 2019

Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Ofd1, a human disease gene, regulates the length and distal structure of centrioles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

ciliary basal body

The BBSome controls IFT assembly and turnaround in cilia

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Ofd1, a human disease gene, regulates the length and distal structure of centrioles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

sperm flagellum

1 reference

9 May 2019

Intraflagellar transport protein IFT20 is essential for male fertility and spermiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

ciliary base

The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

1 reference

9 May 2019

biological process

eye development

1 reference

9 May 2019

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

Notch signaling pathway

1 reference

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

protein localization

1 reference

9 May 2019

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

cilium assembly

4 references

9 May 2019

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Functional characterization of putative cilia genes by high-content analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

cochlea development

1 reference

9 May 2019

Ciliary proteins link basal body polarization to planar cell polarity regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

inner ear receptor cell stereocilium organization

kidney development

2 references

31 January 2018

Phenotypic variations of orpk mutation and chromosomal localization of modifiers influencing kidney phenotype

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

lung development

1 reference

9 May 2019

A crucial role for primary cilia in cortical morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

cardiac septum morphogenesis

1 reference

9 May 2019

A crucial role for primary cilia in cortical morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

cardiac muscle cell differentiation

1 reference

9 May 2019

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

embryonic digit morphogenesis

Loss of the Tg737 protein results in skeletal patterning defects

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Analysis of mouse embryonic patterning and morphogenesis by forward genetics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

A crucial role for primary cilia in cortical morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

spinal cord dorsal/ventral patterning

1 reference

9 May 2019

PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

regulation of feeding behavior

1 reference

9 May 2019

Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

regulation of odontogenesis of dentin-containing tooth

1 reference

9 May 2019

Loss of the Tg737 protein results in skeletal patterning defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

regulation of fat cell differentiation

1 reference

9 May 2019

Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

sperm axoneme assembly

1 reference

9 May 2019

GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

nervous system development

1 reference

9 May 2019

A crucial role for primary cilia in cortical morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

response to fluid shear stress

1 reference

9 May 2019

Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

limb development

1 reference

9 May 2019

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

regulation of protein processing

regulation of autophagosome assembly

1 reference

9 May 2019

Functional interaction between autophagy and ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

forebrain morphogenesis

1 reference

9 May 2019

A crucial role for primary cilia in cortical morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

regulation of smoothened signaling pathway

1 reference

14 February 2019

Role of epidermal primary cilia in the homeostasis of skin and hair follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

heart development

1 reference

9 May 2019

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

telencephalon development

1 reference

9 May 2019

A crucial role for primary cilia in cortical morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

cell projection organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

1 reference

9 May 2019

positive regulation of insulin-like growth factor receptor signaling pathway

1 reference

9 May 2019

Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

heart formation

1 reference

9 May 2019

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

cytoplasmic microtubule organization

1 reference

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

epidermal stem cell homeostasis

1 reference

9 May 2019

Role of epidermal primary cilia in the homeostasis of skin and hair follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

neural precursor cell proliferation

1 reference

9 May 2019

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

epidermis development

1 reference

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

negative regulation of epithelial cell proliferation

1 reference

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

animal organ morphogenesis

1 reference

9 May 2019

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

regulation of cilium assembly

1 reference

9 May 2019

Functional interaction between autophagy and ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

pancreas development

1 reference

9 May 2019

Phenotypic variations of orpk mutation and chromosomal localization of modifiers influencing kidney phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

liver development

smoothened signaling pathway

2 references

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

A crucial role for primary cilia in cortical morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Role of epidermal primary cilia in the homeostasis of skin and hair follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

spermatid nucleus elongation

1 reference

9 May 2019

GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

lung vasculature development

1 reference

9 May 2019

A crucial role for primary cilia in cortical morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

endothelial cell morphogenesis

1 reference

9 May 2019

Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

non-motile cilium assembly

4 references

31 January 2018

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

31 January 2018

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371

primary palate development

1 reference

9 May 2019

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

kidney development

Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Phenotypic variations of orpk mutation and chromosomal localization of modifiers influencing kidney phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

inner ear receptor cell stereocilium organization

Ciliary proteins link basal body polarization to planar cell polarity regulation

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Ciliary proteins link basal body polarization to planar cell polarity regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

non-motile cilium assembly

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

intraciliary transport

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371

has part(s)

tetratricopeptide repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61371

Tetratricopeptide repeat-containing domain

1 reference

InterPro Release 71.0