Hedgehog-interacting protein (Q21982254)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7TN16

Six-bladed beta-propeller, TolB-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7TN16

membrane protein

1 reference

inferred from GOA cell component → membrane

Glucose/Sorbosone dehydrogenase family

1 reference

Folate receptor-like, protein family

1 reference

EGF-like domain, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

1 reference

9 May 2019

catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

1 reference

9 May 2019

protein binding

IPI

1 reference

9 May 2019

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

hedgehog family protein binding

IPI

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

Ensembl genome database project

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

IBA

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

1 reference

9 May 2019

integral component of plasma membrane

1 reference

9 May 2019

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

1 reference

9 May 2019

cell surface

1 reference

9 May 2019

Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

plasma membrane

negative regulation of smoothened signaling pathway

ISO

biological process

regulation of fibroblast growth factor receptor signaling pathway

1 reference

9 May 2019

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

skeletal system morphogenesis

1 reference

9 May 2019

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

animal organ morphogenesis

1 reference

9 May 2019

Combined activities of hedgehog signaling inhibitors regulate pancreas development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

neuroblast proliferation

1 reference

9 May 2019

Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

negative regulation of angiogenesis

NAS

1 reference

9 May 2019

Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

smoothened signaling pathway

NAS

1 reference

14 February 2019

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

negative regulation of signal transduction

ISS

dorsal/ventral pattern formation

ISO

1 reference

9 May 2019

Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

epithelial tube branching involved in lung morphogenesis

1 reference

9 May 2019

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

signal transduction

1 reference

9 May 2019

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

negative regulation of smoothened signaling pathway

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

14 February 2019

Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

negative regulation of smoothened signaling pathway

IBA

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

9 May 2019

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

9 May 2019

Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN16