Dishevelled-binding antagonist of beta-catenin 2 (Q21981322)

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mammalian protein found in Mus musculus

dapper antagonist of catenin 2
Dact2
dapper homolog 2, antagonist of beta-catenin
dapper, antagonist of beta-catenin, homolog 2
dapper homolog 2
mDpr2

Language	Label	Description	Also known as
English	Dishevelled-binding antagonist of beta-catenin 2	mammalian protein found in Mus musculus	dapper antagonist of catenin 2 Dact2 dapper homolog 2, antagonist of beta-catenin dapper, antagonist of beta-catenin, homolog 2 dapper homolog 2 mDpr2

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7TN08

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

delta-catenin binding

determination method or standard

1 reference

16 September 2017

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TN08&geneProductId=UniProtKB:Q7TN08

determination method or standard

transcription factor binding

determination method or standard

1 reference

14 February 2019

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

beta-catenin binding

determination method or standard

1 reference

16 September 2017

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TN08&geneProductId=UniProtKB:Q7TN08

determination method or standard

protein kinase C binding

determination method or standard

1 reference

16 September 2017

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TN08&geneProductId=UniProtKB:Q7TN08

determination method or standard

protein kinase A binding

determination method or standard

1 reference

16 September 2017

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TN08&geneProductId=UniProtKB:Q7TN08

determination method or standard

protein binding

determination method or standard

1 reference

14 February 2019

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

protein kinase C binding

determination method or standard

beta-catenin binding

determination method or standard

protein kinase A binding

determination method or standard

delta-catenin binding

determination method or standard

determination method or standard

1 reference

16 September 2017

A mitochondrial protein compendium elucidates complex I disease biology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TN08&geneProductId=UniProtKB:Q7TN08

determination method or standard

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

determination method or standard

1 reference

14 February 2019

A mitochondrial protein compendium elucidates complex I disease biology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

biological process

negative regulation of cell adhesion

determination method or standard

1 reference

14 February 2019

Accelerated re-epithelialization in Dpr2-deficient mice is associated with enhanced response to TGFbeta signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

regulation of Wnt signaling pathway

determination method or standard

1 reference

16 September 2017

The evolutionally conserved activity of Dapper2 in antagonizing TGF-beta signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TN08&geneProductId=UniProtKB:Q7TN08

determination method or standard

hematopoietic progenitor cell differentiation

determination method or standard

1 reference

14 February 2019

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

inner medullary collecting duct development

determination method or standard

1 reference

14 February 2019

Dact2 is expressed in the developing ureteric bud/collecting duct system of the kidney and controls morphogenetic behavior of collecting duct cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

multicellular organism development

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

epithelial cell morphogenesis

determination method or standard

1 reference

14 February 2019

Dact2 is expressed in the developing ureteric bud/collecting duct system of the kidney and controls morphogenetic behavior of collecting duct cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

skin development

determination method or standard

1 reference

14 February 2019

Accelerated re-epithelialization in Dpr2-deficient mice is associated with enhanced response to TGFbeta signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TN08

determination method or standard

negative regulation of nodal signaling pathway

determination method or standard

regulation of Wnt signaling pathway

determination method or standard

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000051638

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000051638

ENSMUSP00000156781

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000156781

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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